The rates of syphilis are rising in the United States and many high-income nations despite
the availability of screening and effective treatment. 1–4 The diagnosis of syphilis can be …

Since its modern-day nadir of 5979 cases per year, or 2.1 cases per 100 000 population, in
2001, primary and secondary (PS) syphilis incidence has rapidly increased. In 2019, 38 992 …

Syphilis Over the past two decades, the incidence of syphilis has increased sharply. The
courses of both untreated and treated disease can be unpredictable. This review presents …

Syphilis is a sexually transmitted disease caused by the spirochete Treponema pallidum.
The manifestations of this disease are notoriously protean, with different stages occurring …

Syphilis has re-emerged in the United States and elsewhere, and clinicians caring for HIV-
infected patients are challenged with syphilis diagnosis and management decisions. HIV …

Despite advances in the control, diagnosis, and treatment of syphilis, its recognition is ill-
understood or often not considered by dermatologists and other physicians who either have …

Introduction: Syphilis is an important sexually transmitted infection (STI). Despite
inexpensive and effective treatment, few key populations receive syphilis testing. Innovative …

Background: Syphilis, the “great imitator”, presents with a wide range of mucocutaneous and
systemic manifestations, which can mimic many more diseases. Though there has been a …

A panel of experts generated 8 “key questions” in the management of adult syphilis. A
systematic literature review was conducted and tables of evidence were constructed to …

Abstract IMPORTANCE In 2014, 19 999 cases of syphilis were reported in the United States.
Left untreated, syphilis can progress to late-stage disease in about 15% of persons who are …