Computational pharmaceutics-A new paradigm of drug delivery
W Wang, Z Ye, H Gao, D Ouyang - Journal of Controlled Release, 2021 - Elsevier
In recent decades pharmaceutics and drug delivery have become increasingly critical in the
pharmaceutical industry due to longer time, higher cost, and less productivity of new …
pharmaceutical industry due to longer time, higher cost, and less productivity of new …
[HTML][HTML] Thymoquinone (2-Isopropyl-5-methyl-1, 4-benzoquinone) as a chemopreventive/anticancer agent: Chemistry and biological effects
Cancer remains the topmost disorder of the mankind and number of cases is unceasingly
growing at unprecedented rates. Although the synthetic anti-cancer compounds still hold the …
growing at unprecedented rates. Although the synthetic anti-cancer compounds still hold the …
Self-nanoemulsifying drug delivery system (SNEDDS) mediated improved oral bioavailability of thymoquinone: optimization, characterization, pharmacokinetic, and …
Thymoquinone (TQ) is an antioxidant, anti-inflammatory, and hepatoprotective compound
obtained from the black seed oil of Nigella sativa. However, high hydrophobicity, instability …
obtained from the black seed oil of Nigella sativa. However, high hydrophobicity, instability …
Oral bioavailability: issues and solutions via nanoformulations
K Pathak, S Raghuvanshi - Clinical pharmacokinetics, 2015 - Springer
The delivery of drugs through the oral route is regarded as most optimal to achieve desired
therapeutic effects and patient compliance. However, poor pharmacokinetic profiles of oral …
therapeutic effects and patient compliance. However, poor pharmacokinetic profiles of oral …
Nanosizing of drugs: effect on dissolution rate
The solubility, bioavailability and dissolution rate of drugs are important parameters for
achieving in vivo efficiency. The bioavailability of orally administered drugs depends on their …
achieving in vivo efficiency. The bioavailability of orally administered drugs depends on their …
Development of solid self-nanoemulsifying granules (SSNEGs) of ondansetron hydrochloride with enhanced bioavailability potential
S Beg, SS Jena, CN Patra, M Rizwan, S Swain… - Colloids and surfaces B …, 2013 - Elsevier
The current work aims to prepare the solid self-nanoemulsifying granules (SSNEGs) of
ondansetron hydrochloride (ONH) to enhance its oral bioavailability by improving its …
ondansetron hydrochloride (ONH) to enhance its oral bioavailability by improving its …
How nanotechnology can enhance docetaxel therapy
Docetaxel has been recognized as one of the most efficient anticancer drugs over the past
decade; however, its poor water solubility and systemic toxicity have greatly limited its …
decade; however, its poor water solubility and systemic toxicity have greatly limited its …
QbD-based systematic development of novel optimized solid self-nanoemulsifying drug delivery systems (SNEDDS) of lovastatin with enhanced biopharmaceutical …
S Beg, PS Sandhu, RS Batra, RK Khurana, B Singh - Drug delivery, 2015 - Taylor & Francis
Of late, solid self-nanoemulsifying drug delivery systems (S-SNEDDS) have been
extensively sought-after owing to their superior portability, drug loading, stability and patient …
extensively sought-after owing to their superior portability, drug loading, stability and patient …
Therapeutic perspectives of the black cumin component thymoquinone: A review
The dietary phytochemical thymoquinone (TQ), belonging to the family of quinones, mainly
obtained from the black and angular seeds of Nigella sativa, is one of the promising …
obtained from the black and angular seeds of Nigella sativa, is one of the promising …
In vivo evaluation of a self-nanoemulsifying drug delivery system for curcumin
Curcumin has attracted particular attention in recent years due to its great variety of
beneficial biological and pharmacological activities. However, its efficacy has been limited …
beneficial biological and pharmacological activities. However, its efficacy has been limited …