Nintedanib is an orally administered intracellular tyrosine kinase inhibitor approved for
idiopathic pulmonary fibrosis. Differently from oral treatment, dry powder inhalers (DPIs) can …

Background The disorder of circadian rhythm could be a key factor mediating fibrotic lung
disease Therefore, our study aims to determine the diagnostic value of circadian rhythm …

Oral absorption of docetaxel was limited by drug efflux pump p-glycoprotein (P-gp) and
cytochrome P450 enzyme (CYP 450). Therefore, co-loading agent that inhibits P-gp and …

Context: Catha edulis (khat) is a prevalent plant in Yemen and other African regions. In
Yemen and other countries, most people chew this plant, which may change the …

Celecoxib is a specific cyclooxygenase-2 inhibitor with poor solubility and low
bioavailability. A solid selfmicroemulsifying drug delivery system of celecoxib was therefore …

Diltiazem, a calcium ion cellular influx inhibitor is known for its limited and variable
bioavailability. This study is intended to explore the benefits of microemulsion formulation as …

Context: Catha edulis (khat) is a prevalent plant in Yemen and other African regions. In
Yemen and other countries, most people chew this plant, which may change the …

The review goes into great detail about the microemulsions' characteristics, structure, kinds,
theories, characterization, and applications. They may be made easily by mixing the various …

Drug delivery systems are designed for the administration of a pharmaceutical compound to
promote its therapeutic effects in the animal or human body with minimum side effects [1, 2] …

Aims: This study aimed to knowledge and evaluation of the effect of presence of Khat in the
GIT on the bioavailability and efficacy of Tadalafil. Methods: The present study was carried …