Chromatin plasticity and epigenetic memory, fundamental for eukaryotic biology, are
determined by differential/regulated de novo deposition or recycling of pre-existing histones …

Inheritance of chromatin-bound proteins theoretically plays a role in the epigenetic
transmission of cellular phenotypes. Protein segregation during cell division is however …

The CENP-A histone variant epigenetically defines centromeres, where its levels and
locations are precisely maintained through mitotic cell divisions. However, differences in …

Stem cells have emerged as a promising cell source to heal, replace or regenerate tissue
and organs damaged by aging, injury or diseases. The intestinal epithelium is the most …

Tumour evolution is driven by both genetic and epigenetic changes. CENP-A, the
centromeric histone H3 variant, is an epigenetic mark that directly perturbs genetic stability …

Plant cells undergo two types of cell cycles–the mitotic cycle in which DNA replication is
coupled to mitosis, and the endocycle in which DNA replication occurs in the absence of cell …

In many species, centromere identity is specified epigenetically by special nucleosomes
containing a centromere-specific histone H3 variant, designated as CENP-A in humans and …

Adult stem cells are able to support tissue homeostasis by undergoing asymmetric cell
division (ACD) to produce a renewed stem cell and a differentiating cell. Although …

In the germline, stem cells undergo asymmetric cell division (ACD) to give rise to one new
stem cell as well as one daughter cell that differentiates and eventually gives rise to the …

Germline stem cells divide asymmetrically to produce one new daughter stem cell and one
daughter cell that will subsequently undergo meiosis and differentiate to generate the …