[HTML][HTML] Research progress of therapeutic drugs for doxorubicin-induced cardiomyopathy

Y Chen, S Shi, Y Dai - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Doxorubicin (DOX), as a kind of chemotherapy agent with remarkable therapeutic effect, can
be used to treat diverse malignant tumors clinically. Dose-dependent cardiotoxicity is the …

[HTML][HTML] Ginsenosides from Panax ginseng as Key Modulators of NF-κB Signaling Are Powerful Anti-Inflammatory and Anticancer Agents

WY Jang, JY Hwang, JY Cho - International Journal of Molecular …, 2023 - mdpi.com
Nuclear factor kappa B (NF-κB) signaling pathways progress inflammation and immune cell
differentiation in the host immune response; however, the uncontrollable stimulation of NF …

[HTML][HTML] Pro-inflammatory signalling PRRopels cisplatin-induced toxicity

IK Domingo, A Latif, AP Bhavsar - International journal of molecular …, 2022 - mdpi.com
Cisplatin is a platinum-based chemotherapeutic that has long since been effective against a
variety of solid-cancers, substantially improving the five-year survival rates for cancer …

Panax ginseng as Antioxidant and Anti-inflammatory to reduce the Cardiotoxicity of Doxorubicin on rat module

AAH Hany, NM Zainab, HA Ali… - Research Journal of …, 2022 - indianjournals.com
Background Panax ginseng is one of the best ayurvedic plant used for treatment of several
types of disease such as diabetes, improve the libido and hair-lose and as antioxidant also …

[HTML][HTML] Combination of Panax ginseng CA Mey and Febuxostat Boasted Cardioprotective Effects Against Doxorubicin-Induced Acute Cardiotoxicity in Rats

HM Al-Kuraishy, HA Al-Hussaniy… - Frontiers in …, 2022 - frontiersin.org
Doxorubicin (DOX) is an anticancer agent for treating solid and soft tissue malignancies.
However, the clinical use of DOX is restricted by cumulative, dose-dependent cardiotoxicity …

[HTML][HTML] Ginsenoside Rk3 is a novel PI3K/AKT-targeting therapeutics agent that regulates autophagy and apoptosis in hepatocellular carcinoma

L Qu, Y Liu, J Deng, X Ma, D Fan - Journal of Pharmaceutical Analysis, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide.
Ginsenoside Rk3, an important and rare saponin in heat-treated ginseng, is generated from …

[HTML][HTML] The role of thymoquinone in inflammatory response in chronic diseases

Y Liu, L Huang, MY Kim, JY Cho - International Journal of Molecular …, 2022 - mdpi.com
Anti-inflammatory therapies have been shown to be effective in the prevention of various
cardiovascular diseases, tumors, and cancer complications. Thymoquinone (TQ), the main …

[HTML][HTML] Ginsenoside CK, rather than Rb1, possesses potential chemopreventive activities in human gastric cancer via regulating PI3K/AKT/NF-κB signal pathway

Y Wan, D Liu, J Xia, JF Xu, L Zhang, Y Yang… - Frontiers in …, 2022 - frontiersin.org
Ginsenoside Rb1, a main component of ginseng, is often transformed into ginsenoside CK
by intestinal flora to exert various pharmacological activity. However, it remains unclear …

[HTML][HTML] Novel wine in an old bottle: Preventive and therapeutic potentials of andrographolide in atherosclerotic cardiovascular diseases

T Gou, M Hu, M Xu, Y Chen, R Chen, T Zhou… - Journal of …, 2023 - Elsevier
Atherosclerotic cardiovascular disease (ASCVD) frequently results in sudden death and
poses a serious threat to public health worldwide. The drugs approved for the prevention …

[HTML][HTML] Natural compounds: A new perspective on targeting polarization and infiltration of tumor-associated macrophages in lung cancer

X Zhou, X Wang, Q Sun, W Zhang, C Liu, W Ma… - Biomedicine & …, 2022 - Elsevier
With the development in tumor immunology, people are gradually understanding the
complexity and diversity of the tumor microenvironment immune status and its important …