Noninvasive Techniques for Tracking Biological Aging of the Cardiovascular System: JACC Family Series

Z Raisi-Estabragh, L Szabo, A Schuermans… - Cardiovascular …, 2024 - jacc.org
Population aging is one of the most important demographic transformations of our time.
Increasing the “health span”—the proportion of life spent in good health—is a global priority …

Genetic Factors Altering Immune Responses in Atrial Fibrillation: JACC Review Topic of the Week

S Ninni, D Dombrowicz, M de Winther, B Staels… - Journal of the American …, 2024 - jacc.org
Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide and is associated
with a range of adverse clinical outcomes. Accumulating evidence points to inflammatory …

Clonal Hematopoiesis and Incident Heart Failure With Preserved Ejection Fraction

A Schuermans, MC Honigberg, LM Raffield… - JAMA Network …, 2024 - jamanetwork.com
Importance Clonal hematopoiesis of indeterminate potential (CHIP), the age-related clonal
expansion of hematopoietic stem cells with leukemogenic acquired genetic variants, is …

Natural history of clonal haematopoiesis seen in real‐world haematology settings

SA Patel, WK Gerber, R Zheng… - British Journal of …, 2024 - Wiley Online Library
Recursive partitioning of healthy consortia led to the development of the Clonal
Hematopoiesis Risk Score (CHRS) for clonal haematopoiesis (CH); however, in the practical …

Challenges in arrhythmias: anticoagulation in asymptomatic atrial fibrillation, stellate ganglion block in electrical storm, and ECG for prediction of sudden death

F Crea - European Heart Journal, 2024 - academic.oup.com
University in Hamilton, Ontario, Canada, and colleagues. 1 The authors point out that
mineralocorticoid receptor antagonists (MRAs) improve cardiovascular outcomes in a variety …

Clonal haematopoiesis and cardiac arrythmias: rhythm-altering mutations

MA Zuriaga, D Pascual-Figal… - European Heart …, 2024 - academic.oup.com
Ageing is associated with a higher frequency of somatic mutations that drive clonal
haematopoiesis, an emerging risk factor for cardiovascular conditions such as …