Advances in capillary electrophoresis and the implications for drug discovery

CM Ouimet, CI D'amico, RT Kennedy - Expert opinion on drug …, 2017 - Taylor & Francis
Introduction: Many screening platforms are prone to assay interferences that can be avoided
by directly measuring the target or enzymatic product. Capillary electrophoresis (CE) and …

[HTML][HTML] Advances in enzyme substrate analysis with capillary electrophoresis

S Gattu, CL Crihfield, G Lu, L Bwanali, LM Veltri… - Methods, 2018 - Elsevier
Capillary electrophoresis provides a rapid, cost-effective platform for enzyme and substrate
characterization. The high resolution achievable by capillary electrophoresis enables the …

Advances in capillary electrophoretically mediated microanalysis for on‐line enzymatic and derivatization reactions

S Huang, P Paul, P Ramana, E Adams… - …, 2018 - Wiley Online Library
This review summarizes recent developments, applications, and innovations of capillary
electrophoretically mediated microanalysis methods. As a follow up of an earlier review, it …

Advances in screening enzyme inhibitors by capillary electrophoresis

WF Wang, JL Yang - Electrophoresis, 2019 - Wiley Online Library
Capillary electrophoresis (CE) has attracted lots of attention due to its simplicity, low sample
consumption, low solvent volume, high resolution, and high speed. Based on these …

Screening of 5′-methylthioadenosine nucleosidase enzyme inhibitors from traditional Chinese medicine and small molecular compounds by capillary …

K Yu, ME Yue, J Xu, TF Jiang - Chromatographia, 2020 - Springer
A capillary electrophoresis (CE) method was developed for the screening of 5′-
methylthioadenosine nucleosidase (MTAN) inhibitors in traditional Chinese drugs and small …

Capillary electrophoresis in phytochemical analysis (2014–2017)

DD Zhou, Q Zhang, SP Li, FQ Yang - Separation Science Plus, 2018 - Wiley Online Library
This updated review is focused on the applications of CE in phytochemical analysis during
the period of 2014 to April 2018 (about 130 papers were included). The article mainly …

Protein Cross-linking Capillary and Microchip Electrophoresis for Protein-Protein Interaction Analysis

C Ouimet - 2018 - deepblue.lib.umich.edu
Proteins perform their functions as part of multi-protein complexes. These protein complexes
are vital for carrying out and regulating cellular processes. As such, there is a need for tools …