Nanoparticles and its biomedical applications in health and diseases: special focus on drug delivery

N Zahin, R Anwar, D Tewari, MT Kabir, A Sajid… - … Science and Pollution …, 2020 - Springer
Nanotechnology is an emerging technology that deals with nanosized particles possessing
crucial research roles and application. Disciplines like chemistry, biology, physics …

Exosomal delivery of therapeutic modulators through the blood–brain barrier; promise and pitfalls

M Heidarzadeh, Y Gürsoy-Özdemir, M Kaya… - Cell & Bioscience, 2021 - Springer
Nowadays, a large population around the world, especially the elderly, suffers from
neurological inflammatory and degenerative disorders/diseases. Current drug delivery …

Synthesis and potential applications of lipid nanoparticles in medicine

E Musielak, A Feliczak-Guzik, I Nowak - Materials, 2022 - mdpi.com
Currently, carriers of active ingredients in the form of particles of a size measured in
nanometers are the focus of interest of research centers worldwide. So far, submicrometer …

Nanotherapeutics for nose-to-brain drug delivery: an approach to bypass the blood brain barrier

D Lee, T Minko - Pharmaceutics, 2021 - mdpi.com
Treatment of neurodegenerative diseases or other central nervous system (CNS) disorders
has always been a significant challenge. The nature of the blood-brain barrier (BBB) limits …

Lipid nanoparticle-mediated drug delivery to the brain

P Khare, SX Edgecomb, CM Hamadani… - Advanced Drug Delivery …, 2023 - Elsevier
Lipid nanoparticles (LNPs) have revolutionized the field of drug delivery through their
applications in siRNA delivery to the liver (Onpattro) and their use in the Pfizer-BioNTech …

Drug delivery of natural products through nanocarriers for effective breast cancer therapy: A comprehensive review of literature

KM Yap, M Sekar, S Fuloria, YS Wu… - International Journal …, 2021 - Taylor & Francis
Despite recent advances in the diagnosis and treatment of breast cancer (BC), it remains a
global health issue affecting millions of women annually. Poor prognosis in BC patients is …

Recent advances in designing 5-fluorouracil delivery systems: a stepping stone in the safe treatment of colorectal cancer

E Entezar-Almahdi, S Mohammadi-Samani… - International journal …, 2020 - Taylor & Francis
Fluorouracil (5-FU) has become one of the most widely employed antimetabolite
chemotherapeutic agents in recent decades. It is considered a first line antineoplastic agent …

Naringenin nano-delivery systems and their therapeutic applications

M Bhia, M Motallebi, B Abadi, A Zarepour… - Pharmaceutics, 2021 - mdpi.com
Naringenin (NRG) is a polyphenolic phytochemical belonging to the class of flavanones and
is widely distributed in citrus fruits and some other fruits such as bergamot, tomatoes, cocoa …

Recent advances in nano delivery systems for blood-brain barrier (BBB) penetration and targeting of brain tumors

S Reddy, K Tatiparti, S Sau, AK Iyer - Drug Discovery Today, 2021 - Elsevier
Gliomas constitute about 80% of brain tumors and have a meager two-year survival rate.
The treatment options available are very few because of poor prognosis and a lack of …

Hydrogels as drug delivery systems; pros and cons

P Ghasemiyeh, S Mohammadi-Samani - Trends in Pharmaceutical …, 2019 - tips.sums.ac.ir
Hydrogels are cross-linked polymers with hydrophilic groups which enable them to absorb
large amounts of water. Hydrogel based delivery systems have been used for delivery of …