Nanostructured lipid carriers: a promising drug carrier for targeting brain tumours

J Garg, K Pathania, SP Sah, SV Pawar - Future Journal of Pharmaceutical …, 2022 - Springer
Background In recent years, the field of nanotechnology and nanomedicine has transformed
the pharmaceutical industry with the development of novel drug delivery systems that …

Challenges identifying efficacious miRNA therapeutics for cancer

M Segal, FJ Slack - Expert opinion on drug discovery, 2020 - Taylor & Francis
MicroRNAs are a class of small non-coding RNAs (22-23 nucleotides), which regulate gene
expression at the posttranscriptional level and play key roles in tumorigenesis and other …

Nanomedicine-based delivery strategies for breast cancer treatment and management

P Tagde, A Najda, K Nagpal, GT Kulkarni… - International journal of …, 2022 - mdpi.com
Breast cancer is one of the most common types of cancer among women globally. It is
caused by mutations in the estrogen/progesterone receptors and conventional treatment …

Epigallocatechin gallate: Phytochemistry, bioavailability, utilization challenges, and strategies

S Mehmood, M Maqsood, N Mahtab… - Journal of Food …, 2022 - Wiley Online Library
Epigallocatechin gallate (EGCG), a green tea catechin, has gained the attention of current
study due to its excellent health‐promoting effects. It possesses anti‐obesity, antimicrobial …

Current advances in lipid nanosystems intended for topical and transdermal drug delivery applications

N Akombaetwa, AB Ilangala, L Thom, PB Memvanga… - Pharmaceutics, 2023 - mdpi.com
Skin delivery is an exciting and challenging field. It is a promising approach for effective drug
delivery due to its ease of administration, ease of handling, high flexibility, controlled …

Rise of the RNA machines–self-amplification in mRNA vaccine design

JDG Comes, GP Pijlman, TAH Hick - Trends in Biotechnology, 2023 - cell.com
Abstract mRNA vaccines have won the race for early COVID-19 vaccine approval, yet
improvements are necessary to retain this leading role in combating infectious diseases. A …

Chitosan oligosaccharide/alginate nanoparticles as an effective carrier for astaxanthin with improving stability, in vitro oral bioaccessibility, and bioavailability

FN Sorasitthiyanukarn, C Muangnoi, P Rojsitthisak… - Food …, 2022 - Elsevier
Astaxanthin (ATX), a hydrophobic xanthophyll family of carotenoids, has various
advantageous biological activities. Its use as a bioactive compound in functional foods …

[HTML][HTML] Nanomedicines: redefining traditional medicine

W Lu, J Yao, X Zhu, Y Qi - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Nanomedicines offer nanoscale drug delivery system. They offer ways of promising drug
transportation, and address the issues of lack of targeting and permeability of traditional …

Formulation strategies for enhancing the bioavailability of silymarin: the state of the art

A Di Costanzo, R Angelico - Molecules, 2019 - mdpi.com
Silymarin, a mixture of flavonolignan and flavonoid polyphenolic compounds extractable
from milk thistle (Silybum marianum) seeds, has anti-oxidant, anti-inflammatory, anti-cancer …

[HTML][HTML] Recent progress of lipid nanoparticles-based lipophilic drug delivery: focus on surface modifications

Y Seo, H Lim, H Park, J Yu, J An, HY Yoo, T Lee - Pharmaceutics, 2023 - mdpi.com
Numerous drugs have emerged to treat various diseases, such as COVID-19, cancer, and
protect human health. Approximately 40% of them are lipophilic and are used for treating …