Background In the context of the ongoing opioid crisis in the United States and Canada,
opioid agonist therapy (OAT) is the first-line treatment for opioid use disorder. However …

Purpose This national prospective multicohort study examined the relationship between US
adolescents' use of stimulant therapy for attention-deficit/hyperactivity disorder (ADHD) and …

Objectives Increasing knowledge about the toxicology of drug overdose and substance
misuse (DOSM) is important in improving our understanding of the epidemic. We describe …

Rationale The opioid crisis in North America has recently seen a fourth wave, which is
dominated by drug-related deaths due to the combined use of illicitly manufactured fentanyl …

Background: Currently, the capacity to provide buprenorphine treatment (BT) is not sufficient
to treat the growing number of people in the United States with opioid use disorder (OUD) …

Introduction Prescription drug monitoring program (PDMP) use mandates are an important
policy tool to curb nonmedical opioid use. However, data are scarce about their efficacy on …

Background Psychoactive drug combinations are increasingly contributing to overdose
deaths among White and Black Americans. To understand the evolving nature of overdose …

Background This study examined factors associated with treatment recommendations for
patients with a new diagnosis of opioid use disorder (OUD), comparing recommendations …

Aims Stimulant misuse, overdose, and related deaths have increased dramatically.
Identifying and referring individuals with stimulant use disorder to treatment may reduce …

Background While the mandate to check patients' prescription history in Prescription Drug
Monitoring Program (PDMP) database before prescribing/dispensing controlled drugs has …