Abstract The Ehlers‐Danlos syndromes (EDS) are a group of heritable, connective tissue
disorders characterized by joint hypermobility, skin hyperextensibility, and tissue fragility …

The Ehlers–Danlos syndromes comprise a clinically and genetically heterogeneous group
of heritable connective tissue disorders, which are characterized by joint hypermobility, skin …

Abstract The Ehlers–Danlos syndromes (EDS) are a heterogeneous group of hereditary
disorders of connective tissue, with common features including joint hypermobility, soft and …

Chondroitin sulfate proteoglycans and heparan sulfate proteoglycans are major constituents
of the extracellular matrix and the cell surface in the brain. Proteoglycans bind with many …

Joint hypermobility syndrome/Ehlers–Danlos syndrome hypermobility type (JHS/EDS‐HT) is
an evolving and protean disorder mostly recognized by generalized joint hypermobility and …

Ehlers–Danlos syndrome (EDS) describes a group of clinical entities in which the
connective tissue, primarily that of the skin, joint and vessels, is abnormal, although the …

Human syndromes and mouse mutants that exhibit accelerated but bona fide aging in
multiple organs and tissues have been invaluable for the identification of nine denominators …

Defects of the V-type proton (H+) ATPase (V-ATPase) impair acidification and intracellular
trafficking of membrane-enclosed compartments, including secretory granules, endosomes …

Most eukaryotic cells elaborate several proteoglycans critical for transmitting biochemical
signals into and between cells. However, the regulation of proteoglycan biosynthesis is not …

Abstract The Ehlers-Danlos Syndromes comprise a heterogeneous group of rare monogenic
conditions that are characterized by joint hypermobility, skin and vascular fragility and …