Epithelial surfaces protect exposed tissues in the body against intrusion of foreign materials,
including xenobiotics, pollen and microbiota. The relative permeability of the various …

The cochlear implant (CI) is the first effective treatment for deafness and severe losses in
hearing. As such, the CI is now widely regarded as one of the great advances in modern …

Lab-on-a-chip technology is an emerging field evolving from the recent advances of micro-
and nanotechnologies. The technology allows the integration of various components into a …

Progress in drug delivery to the ear has been achieved over the last few years. This review
illustrates the main mechanisms of controlled drug release and the resulting geometry-and …

Die lokale Medikamentenapplikation an das Innenohr bietet eine Reihe von Vorteilen
gegenüber der systemischen Medikamentengabe. Die lokale Applikation erfolgt …

For many years, drug delivery to the inner ear has been a challenge to physicians in the
treatment of inner ear disorders. In the past decade, the field of inner ear drug delivery has …

Meniere's disease (MD) is a severe inner ear condition known by debilitating symptoms,
including spontaneous vertigo, fluctuating and progressive hearing loss, tinnitus, and aural …

Microfabrication technology has enabled the development of novel controlled‐release
devices that possess an integration of structural, mechanical, and perhaps electronic …

Sensorineural losses of hearing and vestibular sensation due to hair cell dysfunction are
among the most common disabilities. Recent preclinical research demonstrates that …

Background: Reliable delivery of agents into the inner ear for therapeutic and diagnostic
purposes remains a challenge. Our novel approach employs microneedles to facilitate …