Effects of substituent and catalyst on the intramolecular Povarov reaction—synthesis of chromenonaphthyridines

S Maiti, SK Panja, K Sadhukhan, J Ghosh… - Tetrahedron …, 2012 - Elsevier
2-(N-Alkenyl-N-aryl) aminochromone-3-carbaldehyde undergoes intramolecular Povarov
reaction with aromatic amines in the presence of Ph3P· HClO4 to produce …

A facile one-pot regioselective synthesis of functionalized novel benzo [f] chromeno [4, 3-b][1, 7] naphthyridines and benzo [f][1, 7] naphthyridines via an imino Diels …

SK Arepalli, B Park, JK Jung, K Lee, H Lee - Tetrahedron letters, 2017 - Elsevier
A novel series of functionalized 13H-benzo [f] chromeno [4, 3-b][1, 7] naphthyridines and 1, 3-
diphenylbenzo [f][1, 7] naphthyridines have been synthesized by an efficient regioselective …

Rapid access to 4-substituted-pyrones and 2 (5H)-furanones via a palladium-catalyzed C–OH bond activation

Y Hu, Q Ding, S Ye, Y Peng, J Wu - Tetrahedron, 2011 - Elsevier
An efficient palladium-catalyzed cross-coupling reaction of 4-hydroxy-pyrone or 4-hydroxy-2
(5H)-furanone with arylboronic acid is described, which affords the 4-substituted-pyrones …

[HTML][HTML] An expedient synthesis, acetylcholinesterase inhibitory activity, and molecular modeling study of highly functionalized hexahydro-1, 6-naphthyridines

AI Almansour, RS Kumar, N Arumugam… - BioMed research …, 2015 - ncbi.nlm.nih.gov
Abstract A series of hexahydro-1, 6-naphthyridines were synthesized in good yields by the
reaction of 3, 5-bis [(E)-arylmethylidene] tetrahydro-4 (1H)-pyridinones with cyanoacetamide …

Naphthyridines with antiviral activity-a review

IP Singh, S Kumar, S Gupta - Medicinal Chemistry, 2017 - ingentaconnect.com
Background: Naphthyridine scaffold is an important pharmacophore in compounds which
have shown various biological activities like antiviral, antimicrobial, anticancer …

Targeting integrase enzyme: a therapeutic approach to combat HIV resistance

D Komal, J Khushboo, S Aaftaab… - Mini Reviews in …, 2020 - ingentaconnect.com
Global Human Immunodeficiency Virus (HIV) statistics by the World Health Organization
(WHO) for the year 2017 was estimated to be 36.9 (31.1-43.9) million. Antiviral drug …

Zinc-Mediated One-Pot Tandem Reaction of Nitriles with Propargyl Bromides: An Access to 3-Alkynylpyridines

Y He, S Guo, X Zhang, X Fan - The Journal of Organic Chemistry, 2014 - ACS Publications
A one-pot procedure for the synthesis of 3-alkynylpyridines via a zinc-mediated tandem
reaction of nitriles with propargyl bromides under extremely mild reaction conditions has …

Solid-phase synthesis of N-substituted pyrrolidinone-tethered N-substituted piperidines via Ugi reaction

Z Liu, A Nefzi - Journal of combinatorial chemistry, 2010 - ACS Publications
Solid-Phase Synthesis of N-Substituted Pyrrolidinone-Tethered N-Substituted Piperidines via
Ugi Reaction | ACS Combinatorial Science ACS ACS Publications C&EN CAS Find my …

Regioselective intramolecular electrophilic substitution reactions involving π-deficient pyridine substrates: a new entry to pyridoquinazolines and benzo [h][1, 6] …

PK Agarwal, M Saifuddin, B Kundu - Tetrahedron, 2010 - Elsevier
Regioselective intramolecular electrophilic substitution reactions have been described in π-
deficient pyridine substrates tethered at C-2 to the aryl amine. The presence and nature of …

Practical Ruthenium-Catalyzed Cyclocarbonylation of Allenyl Alcohols in 2, 4, 6-Collidine Leading to α, β-Unsaturated Lactones: Concise Stereoselective Synthesis of …

M Tsubuki, K Takahashi, T Honda - The Journal of Organic …, 2009 - ACS Publications
We have found that ruthenium-catalyzed cyclocarbonylation of allenyl alcohols in 2, 4, 6-
collidine under atmospheric pressure of carbon monoxide smoothly proceeds to afford α, β …