Involvement of Astrocytes in the Formation, Maintenance, and Function of the Blood–Brain Barrier

G Schiera, CM Di Liegro, G Schirò, G Sorbello… - Cells, 2024 - mdpi.com
The blood–brain barrier (BBB) is a fundamental structure that protects the composition of the
brain by determining which ions, metabolites, and nutrients are allowed to enter the brain …

Long COVID: molecular mechanisms and detection techniques

A Constantinescu-Bercu, A Lobiuc… - International Journal of …, 2023 - mdpi.com
Long COVID, also known as post-acute sequelae of SARS-CoV-2 infection (PASC), has
emerged as a significant health concern following the COVID-19 pandemic. Molecular …

Engineered Wnt7a ligands rescue blood–brain barrier and cognitive deficits in a COVID-19 mouse model

TN Trevino, AB Fogel, G Otkiran, SB Niladhuri… - Brain, 2024 - academic.oup.com
Respiratory infection with SARS-CoV-2 causes systemic vascular inflammation and
cognitive impairment. We sought to identify the underlying mechanisms mediating …

Sex differences in vascular endothelial function related to acute and long COVID-19

KA Kayla, J Bédard-Matteau, S Rousseau… - Vascular …, 2023 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus has been at the
forefront of health sciences research since its emergence in China in 2019 that quickly led to …

Dopamine and its precursor levodopa inactivate SARS-CoV-2 main protease by forming a quinoprotein

M Hao, Y He, T Song, H Guo, MP Rayman… - Free Radical Biology and …, 2024 - Elsevier
Many studies show either the absence, or very low levels of, SARS-CoV-2 viral RNA and/or
antigen in the brain of COVID-19 patients. Reports consistently indicate an abortive infection …

Exploring the Pathophysiology of Long COVID: The Central Role of Low-Grade Inflammation and Multisystem Involvement

E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2024 - mdpi.com
Long COVID (LC), also referred to as Post COVID-19 Condition, Post-Acute Sequelae of
SARS-CoV-2 Infection (PASC), and other terms, represents a complex multisystem disease …

Post-acute sequelae of SARS-CoV-2 infection (Long COVID) in older adults

SJ Russell, K Parker, A Lehoczki, D Lieberman… - GeroScience, 2024 - Springer
Long COVID, also known as PASC (post-acute sequelae of SARS-CoV-2), is a complex
infection-associated chronic condition affecting tens of millions of people worldwide. Many …

[HTML][HTML] Neurological Impact of Respiratory Viruses: Insights into Glial Cell Responses in the Central Nervous System

VP Mora, AM Kalergis, K Bohmwald - Microorganisms, 2024 - mdpi.com
Respiratory viral infections pose a significant public health threat, particularly in children and
older adults, with high mortality rates. Some of these pathogens are the human respiratory …

[HTML][HTML] Blood-brain barrier disruption: a culprit of cognitive decline?

J Che, Y Sun, Y Deng, J Zhang - Fluids and Barriers of the CNS, 2024 - ncbi.nlm.nih.gov
Cognitive decline covers a broad spectrum of disorders, not only resulting from brain
diseases but also from systemic diseases, which seriously influence the quality of life and …

A Disease Hidden in Plain Sight: Pathways and Mechanisms of Neurological Complications of Post-acute Sequelae of COVID-19 (NC-PASC)

A Saxena, J Mautner - Molecular Neurobiology, 2024 - Springer
The global impact of coronavirus disease 2019 (COVID-19) marked by numerous pandemic
peaks is attributed to its high variability and infectious nature, transforming it into a persistent …