Manipulating microbiota in inflammatory bowel disease treatment: Clinical and natural product interventions explored

M Zhu, Y Song, Y Xu, H Xu - International journal of molecular sciences, 2023 - mdpi.com
Inflammatory bowel disease (IBD) is a complex multifactorial chronic inflammatory disease,
that includes Crohn's disease (CD) and ulcerative colitis (UC), having progressively …

[HTML][HTML] The role of NOD2 in intestinal immune response and microbiota modulation: A therapeutic target in inflammatory bowel disease

Z Liu, Y Zhang, T Jin, C Yi, DKW Ocansey… - International …, 2022 - Elsevier
As an intracellular pattern recognition receptor (PPR), the nucleotide-binding
oligomerization domain-containing protein 2 (NOD2) triggers a cascade of immune …

[PDF][PDF] 中药对溃疡性结肠炎肠道微生物代谢产物的作用研究进展

盛天骄, 闫思蒙, 兰威儒, 吴宪澍… - 中国中西医结合消化 …, 2023 - zxyxhen.whuhzzs.com
溃疡性结肠炎的病因尚不明确, 肠道微生物及其代谢产物在本病的发病及缓解中起到了重要作用
. 中药可通过干预肠道菌群及其代谢产物发挥抗溃疡性结肠炎作用, 以往认为清热类药物可以 …

Huangqin decoction ameliorates ulcerative colitis by regulating fatty acid metabolism to mediate macrophage polarization via activating ffar4-ampk-pparα Pathway

M Li, Y Wu, J Qiu, J Lei, M Li, N Xu, Y Liu, Z Jin… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Huangqin Decoction (HQD), a traditional Chinese
medicine (TCM) formula chronicled in Shang Han Lun, is safe and effective for treatment of …

Huang Qin Decoction inhibits the initiation of experimental colitis associated carcinogenesis by controlling the PAD4 dependent NETs

Z Pan, X Xie, Y Chen, S Pan, Z Wu, C Yang, J Liang… - Phytomedicine, 2022 - Elsevier
Background Colorectal cancer is associated with ulcerative colitis (UC). The infiltration of
neutrophils is the main cause of DNA damage produced by inflammation in the intestinal …

Effects of Scutellaria baicalensis Georgi. on intestinal flora in rats with spleen deficiency and damp-heat

Y Wang, Y Cai, F Li, M Zhang, Y Wu, Y Dai… - … of pharmaceutical and …, 2022 - Elsevier
The effects of Scutellaria baicalensis Georgi.(S. baicalensis Georgi.) on the diversity of
intestinal flora in rats with spleen deficiency and damp-heat was explored in the present …

Huang Qin decoction increases SLC6A4 expression and blocks the NFκB-mediated NLRP3/Caspase1/GSDMD pathway to disrupt colitis-associated carcinogenesis

Y Tao, L Wang, X Ye, X Qian, D Pan, X Dong… - Functional & Integrative …, 2024 - Springer
Huang Qin decoction (HQD) is a traditional Chinese medicine formula for treating colitis, but
the effects and molecular mechanism of action of HQD in colitis-associated carcinogenesis …

Polygonatum cyrtonema polysaccharides reshape the gut microbiota to ameliorate dextran sodium sulfate-induced ulcerative colitis in mice

C Lin, D Song, S Wang, Y Chu, C Chi, S Jia… - Frontiers in …, 2024 - frontiersin.org
Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized inflammatory
imbalance, intestinal epithelial mucosal damage, and dysbiosis of the gut microbiota …

Pharmacology Mechanism of Polygonum Bistorta in Treating Ulcerative Colitis Based on Network Pharmacology

J Liu, S Liu, H Cao, B Shi, Q Li, J Shan… - Evidence‐Based …, 2022 - Wiley Online Library
Aim. Ulcerative colitis (UC) is a refractory gastrointestinal disease. The study aimed to
expound the mechanism of Polygonum bistorta (PB) in treating UC by network …

Traditional Chinese medicine treats ulcerative colitis by regulating gut microbiota, signaling pathway and cytokine: Future novel method option for pharmacotherapy

T Wang, X Liu, W Zhang, J Wang, T Wang, W Yue… - Heliyon, 2024 - cell.com
Background Ulcerative colitis (UC) is a chronic non-specific inflammatory disease with
intestinal tract as the main site. The pathogenic of UC has not yet been clarified, and multiple …