Overview of recent developments of pyrazole derivatives as an anticancer agent in different cell line
FE Bennani, L Doudach, Y Cherrah, Y Ramli… - Bioorganic …, 2020 - Elsevier
Pyrazole is a five-membered aromatic heterocyclic ring with two adjacent nitrogen atoms C 3
H 3 N 2 H. The presence of this nucleus in pharmacological agents of various therapeutic …
H 3 N 2 H. The presence of this nucleus in pharmacological agents of various therapeutic …
The therapeutic voyage of pyrazole and its analogs: a review
Pyrazole, a five membered heteroaromatic ring with two nitrogen atoms is of immense
significance. Presence of this nucleus in the pharmacological agents of diverse therapeutic …
significance. Presence of this nucleus in the pharmacological agents of diverse therapeutic …
[HTML][HTML] Functional Pyrazolo[1,5-a]pyrimidines: Current Approaches in Synthetic Transformations and Uses As an Antitumor Scaffold
A Arias-Gomez, A Godoy, J Portilla - Molecules, 2021 - mdpi.com
Pyrazolo [1, 5-a] pyrimidine (PP) derivatives are an enormous family of N-heterocyclic
compounds that possess a high impact in medicinal chemistry and have attracted a great …
compounds that possess a high impact in medicinal chemistry and have attracted a great …
Seeking heterocyclic scaffolds as antivirals against dengue virus
Dengue is one of the most typical viral infection categorized in the Neglected Tropical
Diseases (NTDs). It is transmitted via the female Aedes aegypti mosquito to humans and …
Diseases (NTDs). It is transmitted via the female Aedes aegypti mosquito to humans and …
[HTML][HTML] Structure–activity relationship of benzofuran derivatives with potential anticancer activity
Simple Summary Cancer is the leading cause of death worldwide and responsible for killing
approximately 10 million people per year. Fused heterocyclic ring systems such as …
approximately 10 million people per year. Fused heterocyclic ring systems such as …
Chemistry of Ketene N,S-Acetals: An Overview
L Zhang, J Dong, X Xu, Q Liu - Chemical Reviews, 2016 - ACS Publications
Push–pull alkenes, which bear electron-donating and-accepting group (s) at both termini of
a C C double bond, respectively, are of interest not only for their unique electronic …
a C C double bond, respectively, are of interest not only for their unique electronic …
Domino CH sulfonylation and pyrazole annulation for fully substituted pyrazole synthesis in water using hydrophilic enaminones
Y Guo, G Wang, L Wei, JP Wan - The Journal of Organic …, 2019 - ACS Publications
The cascade reactions between NH 2-functionalized enaminones and sulfonyl hydrazines
have been developed for the synthesis of fully substituted pyrazoles. By making use of the …
have been developed for the synthesis of fully substituted pyrazoles. By making use of the …
Recent advanced in bioactive systems containing pyrazole fused with a five membered heterocycle
D Raffa, B Maggio, MV Raimondi, S Cascioferro… - European journal of …, 2015 - Elsevier
In this review we report the recent advances in bioactive system containing pyrazole fused
with a five membered heterocycle, covering the time span of the last decade. All of them are …
with a five membered heterocycle, covering the time span of the last decade. All of them are …
Cobalt-catalyzed Markovnikov selective sequential hydrogenation/hydrohydrazidation of aliphatic terminal alkynes
Here, we reported for the first time a mechanistically distinctive cobalt-catalyzed
Markovnikov-type sequential semihydrogenation/hydrohydrazidation of aliphatic terminal …
Markovnikov-type sequential semihydrogenation/hydrohydrazidation of aliphatic terminal …
H4SiW12O40-catalyzed cyclization of epoxides/aldehydes and sulfonyl hydrazides: An efficient synthesis of 3, 4-disubstituted 1H-pyrazoles
G Yang, X Xie, M Cheng, X Gao, X Lin, K Li… - Chinese Chemical …, 2022 - Elsevier
A simple and efficient method for the synthesis of pyrazoles through a silicotungstic acid (H 4
SiW 12 O 40)-catalyzed cyclization of epoxides/aldehydes and sulfonyl hydrazides has been …
SiW 12 O 40)-catalyzed cyclization of epoxides/aldehydes and sulfonyl hydrazides has been …