[PDF][PDF] The role of hepatokines in NAFLD

N Stefan, F Schick, AL Birkenfeld, HU Häring, MF White - Cell metabolism, 2023 - cell.com
Non-alcoholic fatty liver disease (NAFLD) is not only a consequence of insulin resistance,
but it is also an important cause of insulin resistance and major non-communicable diseases …

The impact of insulin resistance on the kidney and vasculature

F Artunc, E Schleicher, C Weigert, A Fritsche… - Nature Reviews …, 2016 - nature.com
Insulin resistance is a systemic disorder that affects many organs and insulin-regulated
pathways. The disorder is characterized by a reduced action of insulin despite increased …

NAFLD, and cardiovascular and cardiac diseases: Factors influencing risk, prediction and treatment

G Targher, KE Corey, CD Byrne - Diabetes & metabolism, 2021 - Elsevier
Background and aim Non-alcoholic fatty liver disease (NAFLD), affecting up to around 30%
of the world's adult population, causes considerable liver-related and extrahepatic morbidity …

The role of hepatokines in metabolism

N Stefan, HU Häring - Nature Reviews Endocrinology, 2013 - nature.com
The liver is known to be involved in the natural history of the ongoing epidemics of type 2
diabetes mellitus and cardiovascular disease. In particular, the liver has a role in increased …

Systemic sclerosis in adults. Part I: Clinical features and pathogenesis

R Jerjen, M Nikpour, T Krieg, CP Denton… - Journal of the American …, 2022 - Elsevier
Systemic sclerosis (SSc), also referred to as systemic scleroderma or scleroderma, is a rare,
complex immune-mediated connective tissue disease characterized by progressive skin …

Mendelian randomization studies: a review of the approaches used and the quality of reporting

AGC Boef, OM Dekkers… - International journal of …, 2015 - academic.oup.com
Background: Mendelian randomization (MR) studies investigate the effect of genetic
variation in levels of an exposure on an outcome, thereby using genetic variation as an …

Fetuin-A regulation of calcified matrix metabolism

W Jahnen-Dechent, A Heiss, C Schäfer… - Circulation …, 2011 - Am Heart Assoc
The final step of biomineralization is a chemical precipitation reaction that occurs
spontaneously in supersaturated or metastable salt solutions. Genetic programs direct …

[HTML][HTML] Non-alcoholic fatty liver disease and cardiovascular disease: assessing the evidence for causality

MCGJ Brouwers, N Simons, CDA Stehouwer, A Isaacs - Diabetologia, 2020 - Springer
Non-alcoholic fatty liver disease (NAFLD) is highly prevalent among individuals with type 2
diabetes. Although epidemiological studies have shown that NAFLD is associated with …

Coronary artery disease and cardiovascular outcomes in patients with non-alcoholic fatty liver disease

VWS Wong, GLH Wong, GWK Yip, AOS Lo… - Gut, 2011 - gut.bmj.com
Objective Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic
syndrome and is associated with cardiovascular risk. The aim of this study was to determine …

Effects of a three‐month combined exercise programme on fibroblast growth factor 21 and fetuin‐A levels and arterial stiffness in obese women

SJ Yang, HC Hong, HY Choi, HJ Yoo… - Clinical …, 2011 - Wiley Online Library
Objective We examined the relationship between brachial‐ankle pulse wave velocity
(baPWV) reflecting arterial stiffness and the levels of novel hepatokines fibroblast growth …