Chemical synthesis of glycosaminoglycans
M Mende, C Bednarek, M Wawryszyn, P Sauter… - Chemical …, 2016 - ACS Publications
Glycosaminoglycans (GAGs) as one major part of the glycocalyx are involved in many
essential biological cell processes, as well as in many courses of diseases. Because of the …
essential biological cell processes, as well as in many courses of diseases. Because of the …
Control of protein immobilization: Coupling immobilization and site-directed mutagenesis to improve biocatalyst or biosensor performance
K Hernandez, R Fernandez-Lafuente - Enzyme and microbial technology, 2011 - Elsevier
Mutagenesis and immobilization are usually considered to be unrelated techniques with
potential applications to improve protein properties. However, there are several reports …
potential applications to improve protein properties. However, there are several reports …
Modulation of enzymes selectivity via immobilization
JM Palomo - Current Organic Synthesis, 2009 - ingentaconnect.com
Enzymes are very versatile catalysts in organic chemistry, although in many occasions they
present very low selectivity towards non-natural or artificial compounds. A simple strategy …
present very low selectivity towards non-natural or artificial compounds. A simple strategy …
Synthesis of N-Acetyllactosamine and N-Acetyllactosamine-Based Bioactives
N-Acetyllactosamine (LacNAc) or more specifically β-d-galactopyranosyl-1, 4-N-acetyl-d-
glucosamine is a unique acyl-amino sugar and a key structural unit in human milk …
glucosamine is a unique acyl-amino sugar and a key structural unit in human milk …
Chemical and chemoenzymatic synthesis of glycosyl-amino acids and glycopeptides related to Trypanosoma cruzi mucins
This study describes the synthesis of the α-and β-linked N-acetyllactosamine (Galp-β-1, 4-
GlcNAc; LacNAc) glycosides of threonine (LacNAc-Thr). LacNAc-α-Thr was prepared by …
GlcNAc; LacNAc) glycosides of threonine (LacNAc-Thr). LacNAc-α-Thr was prepared by …
Enzymatic synthesis of dimeric glycomimetic ligands of NK cell activation receptors
A Drozdová, P Bojarová, K Křenek, L Weignerová… - Carbohydrate …, 2011 - Elsevier
This work reveals new structural relationships in the complex process of the interaction
between activation receptors of natural killer cells (rat NKR-P1, human CD69) and novel …
between activation receptors of natural killer cells (rat NKR-P1, human CD69) and novel …
Synthesis of LacdiNAc-terminated glycoconjugates by mutant galactosyltransferase–A way to new glycodrugs and materials
P Bojarová, K Křenek, K Wetjen, K Adamiak… - …, 2009 - academic.oup.com
Abstract Human placental β1, 4-galactosyltransferase-I (EC 2.4. 1.38) transfers the
galactosyl moiety from UDP-Gal to various GlcNAc or Glc acceptors in vivo. Here, we …
galactosyl moiety from UDP-Gal to various GlcNAc or Glc acceptors in vivo. Here, we …
Anticancer secondary metabolites: from ethnopharmacology and identification in native complexes to biotechnological studies in species of genus Astragalus L. and …
I Ionkova, A Shkondrov, Y Zarev, E Kozuharova… - Current Issues in …, 2022 - mdpi.com
Some of the most effective anticancer compounds are still derived from plants since the
chemical synthesis of chiral molecules is not economically efficient. Rapid discovery of lead …
chemical synthesis of chiral molecules is not economically efficient. Rapid discovery of lead …
Isolation and Structure Elucidation of Glucosylated Colchicinoids from the Seeds of Gloriosa superba by LC-DAD-SPE-NMR
Y Zarev, K Foubert, I Ionkova, S Apers… - Journal of natural …, 2017 - ACS Publications
Four new colchicinoids were isolated from the seeds of Gloriosa superba together with the
known compounds colchicoside (4) and 3-de-O-methylcolchicine-3-O-β-d-glucopyranosyl …
known compounds colchicoside (4) and 3-de-O-methylcolchicine-3-O-β-d-glucopyranosyl …
Immobilization of the recombinant xylanase B (XynB) from the hyperthermophilic Thermotoga maritima on metal-chelate Eupergit C 250L
L Li, Y Zhu, Z Huang, Z Jiang, W Chen - Enzyme and microbial technology, 2007 - Elsevier
Immobilization of XynB from the hyperthermophilic Thermotoga maritima on nickel-chelate
IDA (iminodiacetic acid disodium salt monohydrate)-Eupergit C 250L (Ni-E, nickel-chelate …
IDA (iminodiacetic acid disodium salt monohydrate)-Eupergit C 250L (Ni-E, nickel-chelate …