Chiral amines are valuable building blocks for the pharmaceutical industry. ω-TAms have
emerged as an exciting option for their synthesis, offering a potential “green alternative” to …

Ecological and efficient alternatives to industrial processes have sparked interest for using
microorganisms and enzymes as biocatalysts. One of the difficulties is finding candidates …

Transaminases have attracted considerable interest in their use as biocatalysts for the
synthesis of compounds containing chiral amine units, which are widespread within the …

Aminotransferases (ATs) are pyridoxal 5′-phosphate–dependent enzymes that catalyze
the transamination reactions between amino acid donor and keto acid acceptor substrates …

Enzymes that use the cofactor pyridoxal phosphate (PLP) constitute a ubiquitous class of
biocatalysts. Here, we analyse their variety and genomic distribution as an example of the …

In this review we analyse structure/sequence–function relationships for the superfamily of
PLP-dependent enzymes with special emphasis on class III transaminases. Amine …

Pyridoxal 5′-phosphate (PLP) functions as a coenzyme in many enzymatic processes,
including decarboxylation, deamination, transamination, racemization, and others. Enzymes …

Adaptation to acid stress is an important factor in the transmission of intestinal microbes. The
enterobacterium Escherichia coli uses a range of physiological, metabolic, and proton …

The use of transaminases to access pharmaceutically relevant chiral amines is an attractive
alternative to transition-metal-catalysed asymmetric chemical synthesis. However, one major …

Lactic acid bacteria (LAB) constitute a diverse group of Gram positive obligately fermentative
microorganisms which include both beneficial and pathogenic strains. LAB generally have …