Hypervirulent Klebsiella pneumoniae – clinical and molecular perspectives

JE Choby, J Howard‐Anderson… - Journal of internal …, 2020 - Wiley Online Library
Hypervirulent Klebsiella pneumoniae (hvKp) has emerged as a concerning global
pathogen. hvKp is more virulent than classical K. pneumoniae (cKp) and capable of causing …

[HTML][HTML] Drug efflux pump inhibitors: a promising approach to counter multidrug resistance in Gram-negative pathogens by targeting AcrB protein from AcrAB-TolC …

R Alenazy - Biology, 2022 - mdpi.com
Simple Summary Multidrug-resistant bacterial infections, especially that caused by Gram-
negative bacteria, have posed serious health issues worldwide. Bacteria have different …

[HTML][HTML] ESCMID/EUCIC clinical practice guidelines on perioperative antibiotic prophylaxis in patients colonized by multidrug-resistant Gram-negative bacteria before …

E Righi, NT Mutters, X Guirao, MD Del Toro… - Clinical Microbiology …, 2023 - Elsevier
Scope The aim of the guidelines is to provide recommendations on perioperative antibiotic
prophylaxis (PAP) in adult inpatients who are carriers of multidrug-resistant Gram-negative …

In vitro activity of imipenem/relebactam and ceftolozane/tazobactam against clinical isolates of gram-negative bacilli with difficult-to-treat resistance and multidrug …

JA Karlowsky, SH Lob, J Raddatz… - Clinical Infectious …, 2021 - academic.oup.com
Background Multidrug-resistant (MDR) bacteria are frequently defined using the criteria
established by Magiorakos et al [Clin Microbiol Infect 2012; 18: 268–81]. Difficult-to-treat …

How to tailor recommendations on the treatment of multi-drug resistant Gram-negative infections at country level integrating antibiotic stewardship principles within the …

E Carrara, PA Grossi, A Gori… - The Lancet Infectious …, 2024 - thelancet.com
Promoting the optimal use of antibiotics through evidence-based recommendations should
be regarded as a crucial step in the global fight against antimicrobial resistance. Within this …

[HTML][HTML] Multidrug Resistant Acinetobacter baumannii: Resistance by Any Other Name Would Still be Hard to Treat

DA Butler, M Biagi, X Tan, S Qasmieh… - Current infectious …, 2019 - Springer
Abstract Purpose of Review Acinetobacter baumannii (AB) is an infamous nosocomial
pathogen with a seemingly limitless capacity for antimicrobial resistance, leading to few …

[HTML][HTML] Needles in haystacks: reevaluating old paradigms for the discovery of bacterial secondary metabolites

MG Chevrette, J Handelsman - Natural Product Reports, 2021 - pubs.rsc.org
Covering: up to 2021 Natural products research is in the midst of a renaissance ushered in
by a modern understanding of microbiology and the technological explosions of genomics …

Carbapenemase-producing Enterobacteriaceae in transplant patients

M Giannella, M Bartoletti, M Conti… - Journal of Antimicrobial …, 2021 - academic.oup.com
Carbapenemase-producing Enterobacteriaceae (CPE) are a serious public health concern
and represent a major threat to immunocompromised hosts, including solid organ (SOT) and …

A metagenomic prospective cohort study on gut microbiome composition and clinical infection in small bowel transplantation

A Madhav, R Bousfield, J Pereira-Dias, C Cormie… - Gut …, 2024 - Taylor & Francis
Two-thirds of small-bowel transplantation (SBT) recipients develop bacteremia, with the
majority of infections occurring within 3 months post-transplant. Sepsis-related mortality …

[HTML][HTML] Bacterial and viral infection and sepsis in kidney transplanted patients

A Mella, F Mariano, C Dolla, E Gallo, AM Manzione… - Biomedicines, 2022 - mdpi.com
Kidney transplanted patients are a unique population with intrinsic susceptibility to viral and
bacterial infections, mainly (but not exclusively) due to continuous immunosuppression. In …