Monitoring of biologically active substances in clinical samples by capillary and microchip electrophoresis with contactless conductivity detection: A review

P Tůma - Analytica chimica acta, 2022 - Elsevier
Contactless conductivity detection (C4D) as a universal detection technique plays an
important role in combination with efficient electrophoretic separation carried out in …

[HTML][HTML] Capillary gel electrophoresis of proteins: historical overview and recent advances

L Hajba, S Jeong, DS Chung, A Guttman - TrAC Trends in Analytical …, 2023 - Elsevier
This review summarizes the fundamental principles, basic methodologies, strength and
weaknesses of capillary gel electrophoresis of proteins by providing both a short historical …

Capillary electrophoresis‐mass spectrometry for intact protein analysis: Pharmaceutical and biomedical applications (2018–March 2023)

K Maráková, M Opetová… - Journal of Separation …, 2023 - Wiley Online Library
Capillary electrophoresis is recognized as a valued separation technique for its high
separation efficiency, low sample consumption, good economic and ecological aspects …

What is the role of current mass spectrometry in pharmaceutical analysis?

M Khalikova, J Jireš, O Horáček… - Mass Spectrometry …, 2024 - Wiley Online Library
The role of mass spectrometry (MS) has become more important in most application
domains in recent years. Pharmaceutical analysis is specific due to its stringent regulation …

Recent developments and applications of capillary and microchip electrophoresis in proteomics and peptidomics (mid‐2018–2022)

S Štěpánová, V Kašička - Journal of Separation Science, 2023 - Wiley Online Library
This review gives a wide overview of recent advances and applications of capillary
electrophoresis and microchip capillary electrophoresis methods in the fields of proteomics …

[HTML][HTML] Advances and applications of capillary electromigration methods in the analysis of therapeutic and diagnostic recombinant proteins–A Review

H Stutz - Journal of Pharmaceutical and Biomedical Analysis, 2023 - Elsevier
This review provides a comprehensive overview of methodological advances and
applications of CE in the analysis and characterization of recombinant therapeutic and …

A feasibility study on the use of hydrophobic eutectic solvents as pseudo-stationary phases in capillary electrophoresis for chiral separations

A Li, S Xue, Y Xu, S Ding, D Wen, Q Zhang - Analytica Chimica Acta, 2023 - Elsevier
A critical challenge in using deep eutectic solvents (DESs) in capillary electrophoresis (CE)
is to develop separation systems in which a DES can really work as a single entity. To …

Chiral separation by capillary electrokinetic chromatography with hydrophobic deep eutectic solvents as pseudo-stationary phases

Y Xu, A Li, S Xue, S Ding, Q Zhang - Talanta, 2023 - Elsevier
This study demonstrated for the first time that hydrophobic deep eutectic solvents (HDESs)
can be used in capillary electrophoresis (CE) for chiral separations. We found that the an …

Mass spectrometry-based charge heterogeneity characterization of therapeutic mAbs with imaged capillary isoelectric focusing and ion-exchange chromatography as …

G Wu, C Yu, W Wang, J Du, Z Fu, G Xu, M Li… - Analytical …, 2023 - ACS Publications
Imaged capillary isoelectric focusing (icIEF) and ion-exchange chromatography (IEX) are
two essential techniques that are routinely used for charge variant analysis of therapeutic …

[HTML][HTML] Comparative study on the deamidation of three recombinant human insulins using capillary electrophoresis

M Andrasi, G Vishwakarma, R Szabo, C Nagy… - … of Chromatography A, 2023 - Elsevier
The applicability of capillary zone electrophoresis (CZE) for the separation of different
recombinant human insulins and their deamidated isoforms was studied. The high resolving …