Hematopoietic mosaic loss of Y chromosome (mLOY) is associated with increased risk of
mortality and age-related diseases in men, but the causal and mechanistic relationships …

Satellite DNAs are present on every chromosome in the cell and are typically enriched in
repetitive, heterochromatic parts of the human genome. Sex chromosomes represent a …

Until a few years ago, it was believed that the gradual mosaic loss of the Y chromosome
(mLOY) was a normal age-related process. However, it is now known that mLOY is …

Mosaic loss of chromosome Y (mLOY) is a common ageing-related somatic event and has
been previously associated with Alzheimer's disease (AD). However, mLOY estimation from …

The development of new biomarkers for prediction and early detection of human diseases,
as well as for monitoring the response to therapy is one of the most relevant areas of modern …

The Y chromosome has long been considered to be a “genetic wasteland” harboring only
few genes essentially involved in male sex development and spermatogenesis. However …

Mosaic loss of chromosome Y (mLOY) is a common ageing-related somatic event occurring
exclusively in men and has been previously associated with Alzheimer's disease (AD) …

Аннотация Одно из наиболее актуальных направлений современной генетики и
геномики человека–разработка новых биомаркеров для прогнозирования и раннего …

Мета робoти–аналіз сучасних поглядів щодо причин і маніфестації процесів старіння;
узагальнення цих даних сприятиме розробленню стратегії з уповільнення перебігу …

Висновки. Сучасні досягнення у високопродуктивній геноміці, транскриптоміці,
протеоміці й метаболоміці дають змогу охарактеризувати, кількісно визначити тисячі …