Measuring particle size distribution of nanoparticle enabled medicinal products, the joint view of EUNCL and NCI-NCL. A step by step approach combining orthogonal …

F Caputo, J Clogston, L Calzolai, M Rösslein… - Journal of Controlled …, 2019 - Elsevier
The particle size distribution (PSD) and the stability of nanoparticles enabled medicinal
products (NEP) in complex biological environments are key attributes to assess their quality …

Towards more accurate bioimaging of drug nanocarriers: turning aggregation-caused quenching into a useful tool

J Qi, X Hu, X Dong, Y Lu, H Lu, W Zhao… - Advanced Drug Delivery …, 2019 - Elsevier
One of the current challenges in the monitoring of drug nanocarriers lies in the difficulties in
discriminating the carrier-bound signals from the bulk signals of probes. Environment …

Current hurdles to the translation of nanomedicines from bench to the clinic

S Đorđević, MM Gonzalez, I Conejos-Sánchez… - Drug delivery and …, 2022 - Springer
The field of nanomedicine has significantly influenced research areas such as drug delivery,
diagnostics, theranostics, and regenerative medicine; however, the further development of …

Mechanistic understanding of protein Corona formation around nanoparticles: old puzzles and new insights

K Nienhaus, GU Nienhaus - Small, 2023 - Wiley Online Library
Although a wide variety of nanoparticles (NPs) have been engineered for use as disease
markers or drug delivery agents, the number of nanomedicines in clinical use has hitherto …

Polymer-tethered nanoparticles: From surface engineering to directional self-assembly

NN Zhang, X Shen, K Liu, Z Nie… - Accounts of Chemical …, 2022 - ACS Publications
Conspectus Current interest in nanoparticle ensembles is motivated by their collective
synergetic properties that are distinct from or better than those of individual nanoparticles …

A single-molecule view at nanoparticle targeting selectivity: Correlating ligand functionality and cell receptor density

L Woythe, P Madhikar, N Feiner-Gracia, C Storm… - ACS …, 2022 - ACS Publications
Antibody-functionalized nanoparticles (NPs) are commonly used to increase the targeting
selectivity toward cells of interest. At a molecular level, the number of functional antibodies …

[HTML][HTML] A quantitative view on multivalent nanomedicine targeting

L Woythe, NB Tito, L Albertazzi - Advanced drug delivery reviews, 2021 - Elsevier
Although the concept of selective delivery has been postulated over 100 years ago, no
targeted nanomedicine has been clinically approved so far. Nanoparticles modified with …

New nanotechnologies for the treatment and repair of skin burns infections

EB Souto, AF Ribeiro, MI Ferreira, MC Teixeira… - International journal of …, 2020 - mdpi.com
Burn wounds are highly debilitating injuries, with significant morbidity and mortality rates
worldwide. In association with the damage of the skin integrity, the risk of infection is …

Designing paper-based immunoassays for biomedical applications

DR Hristov, C Rodriguez-Quijada, J Gomez-Marquez… - Sensors, 2019 - mdpi.com
Paper-based sensors and assays have been highly attractive for numerous biological
applications, including rapid diagnostics and assays for disease detection, food safety, and …

[HTML][HTML] Nanoparticles for biomedical applications: exploring and exploiting molecular interactions at the nano-bio interface

K Nienhaus, H Wang, GU Nienhaus - Materials Today Advances, 2020 - Elsevier
Nanomaterials have high potential as powerful tools for nanomedicine in a wide range of
most promising applications as highly specific devices for diagnosis and therapy. Yet …