These guidelines are intended for use by infectious disease specialists, orthopedic
surgeons, neurosurgeons, radiologists, and other healthcare professionals who care for …

Background Chronic osteomyelitis is generally treated with antibiotics and surgical
debridement but can persist intermittently for years with frequent therapeutic failure or …

Chronic posttraumatic osteomyelitis and infected nonunion of the tibia are complex
problems that result in considerable morbidity and can threaten viability of the limb …

We studied prospectively a consecutive series of 50 patients with chronic osteomyelitis.
Patients were allocated to the following treatment groups: 1) wide resection, with a …

Objectives: We sought to compare the effectiveness of an antibiotic-impregnated
bioabsorbable bone substitute (BBS, tobramycin-impregnated medical-grade calcium …

Open fractures are associated with an increased risk of infection and healing complications.
Management of open fractures is based on the following principles: assessment of the …

Osteomyelitis is traditionally staged by the Waldvogel classification system. The Waldvogel
classification is an etiologic system and does not readily lend itself to guiding surgical or …

Chronic osteomyelitis is refractory to nonsurgical treatment due to a resilient, infective nidus
that harbors sessile, matrix-protected pathogens bound to substrate surfaces within the …

Bone infection in adults is a potentially devastating complication following trauma or surgery.
The clinician should diagnose osteomyelitis based on certain clinical manifestations and on …

Intramedullary infection in long bones represents a complex clinical challenge, with an
increasing incidence due to the increasing use of intramedullary fixation. We report a …