The fallopian tube,“precursor escape” and narrowing the knowledge gap to the origins of high-grade serous carcinoma

TR Soong, BE Howitt, N Horowitz, MR Nucci… - Gynecologic …, 2019 - Elsevier
Most ovarian carcinomas are high-grade serous carcinomas (HGSC) that contain TP53
mutations, present at advanced stage, and eventually become resistant to chemotherapy …

Evidence for lineage continuity between early serous proliferations (ESPs) in the Fallopian tube and disseminated high‐grade serous carcinomas

TR Soong, BE Howitt, A Miron… - The Journal of …, 2018 - Wiley Online Library
The distal Fallopian tube is a site of origin for many 'ovarian'high‐grade serous carcinomas
(HGSCs) with intraepithelial carcinomas (STICs) that share identical TP53 mutations with …

[PDF][PDF] Frontiers in the pathology and pathogenesis of ovarian cancer: cancer precursors and" Precursor Escape"

TR Soong, DM Dinulescu, W Xian, CP Crum - … /Oncology Clinics of North …, 2018 - Elsevier
This article summarizes the pathogenesis of ovarian carcinoma and focuses on the paradox
of high grade serous carcinogenesis, where the fallopian tube has emerged as the prime …

[HTML][HTML] Unexpected primary fallopian tube carcinoma during gynecological operations: Clinicopathological and prognostic factors analyses of 67 cases

M Sun, L Bao, H Shen, M Ji, L Yao, X Yi… - Taiwanese journal of …, 2019 - Elsevier
Objective The aim of the study was to analyze the clinicopathologic features, the survival
rate, and the prognostic factors of women with unexpected primary fallopian tube carcinoma …

Prophylactic salpingectomy during hysterectomy for benign disease: a prospective study to evaluate high-grade serous ovarian carcinoma precursors

G Tchartchian, B Bojahr, L Heils, H Krentel… - Journal of Clinical …, 2022 - mdpi.com
Recent findings suggest that high-grade serous ovarian cancer can originate in the fallopian
tube. Not only has that made the identification of precursor lesions pivotal in early detection …

Prevalence of precursor lesions (P53 signature, SCOUT, STIL, STIC) in fallopian tubes resected for non-neoplastic causes

S Tewari, V Misra, V Kumar, RR Mishra… - Indian Journal of …, 2022 - journals.lww.com
Background: High-grade pelvic serous carcinoma is a common cause of death in women
worldwide and India. Recent evidence has clearly implicated the changes in the mucosa of …

Primary fallopian tube cancer: a literature review

D Sumtsov - Eastern Ukrainian Medical Journal, 2023 - eumj.med.sumdu.edu.ua
Introduction. This literature review presents an analysis of diagnostic methods and treatment
of a relatively rare and highly malignant tumor–primary fallopian tube cancer, which is poorly …

Primary Fallopian Tube Cancer: A Rare Interesting Case Report

MM Boob, NN Chavan, D Kapote… - Indian Journal of …, 2024 - Springer
Discussion Pelvic (extrauterine) high-grade serous carcinomas including ovarian, tubal and
primary peritoneal serous carcinomas have increased death: incidence ratio due to …

Prevention of ovarian, fallopian tube, and peritoneal serous cancers (literature review)

D Sumtsov - Eastern Ukrainian Medical Journal, 2024 - eumj.med.sumdu.edu.ua
Introduction. This literature review presents an analysis of the incidence and state of
prevention of highly malignant tumors that are difficult to diagnose: serous ovarian cancer …

Mагнітно-резонансна та комп'ютерна томографія у діагностиці первинного раку маткових труб

Д Сумцов, А Скульбеда, ГО Сумцов, ІМ Нікітіна - 2024 - essuir.sumdu.edu.ua
Первинний рак маткових труб (ПРМТ)–рідкісне, дуже злоякісне та складне для
діагностики захворювання. Він становить 1, 3–1, 8% усіх випадків раку жіночих статевих …