Palytoxin action on the Na+, K+-ATPase and the disruption of ion equilibria in biological systems
GP Rossini, A Bigiani - Toxicon, 2011 - Elsevier
Palytoxin-group toxins (PlTX) exert their potent biological activity by altering mechanisms of
ion homeostasis in excitable and non-excitable tissues. This review will describe major …
ion homeostasis in excitable and non-excitable tissues. This review will describe major …
Marine toxins and the cytoskeleton: a new view of palytoxin toxicity
MC Louzao, IR Ares, E Cagide - The FEBS Journal, 2008 - Wiley Online Library
Palytoxin is a marine toxin first isolated from zoanthids (genus Palythoa), even though
dinoflagellates of the genus Ostreopsis are the most probable origin of the toxin. Ostreopsis …
dinoflagellates of the genus Ostreopsis are the most probable origin of the toxin. Ostreopsis …
Production of Functionally Active Palytoxin-like Compounds by Mediterranean Ostreopsis cf. siamensis
E Cagide, MC Louzao, B Espiña, MR Vieytes… - Cellular Physiology and …, 2009 - karger.com
Background and purpose: Dinoflagellates from the genus Ostreopsis have been related to
the production of palytoxin and analogues. Based on that, this paper describes functional …
the production of palytoxin and analogues. Based on that, this paper describes functional …
Mechanism of palytoxin-induced Na+ influx into cultured bovine adrenal chromaffin cells: Possible involvement of Na+ H+ exchange system
M Yoshizumi, H Houchi, Y Ishimura, Y Masuda… - Neuroscience …, 1991 - Elsevier
To elucidate the mechanism of palytoxin (PTX)-induced Na+ influx, we examined the effect
of amiloride, an inhibitor of Na+ H+-antiporter, on PTX-induced Na+ influx into cultured …
of amiloride, an inhibitor of Na+ H+-antiporter, on PTX-induced Na+ influx into cultured …
Marine toxins potently affecting neurotransmitter release
FA Meunier, C Mattei, J Molgó - Marine Toxins as Research Tools, 2009 - Springer
Synapses are specialised structures where interneuronal communication takes place. Not
only brain function is absolutely dependent on synaptic activity, but also most of our organs …
only brain function is absolutely dependent on synaptic activity, but also most of our organs …
Palytoxin causes nonoxidative necrotic damage to PC12 cells in culture
T Sagara, N Nishibori, M Itoh… - Journal of Applied …, 2013 - Wiley Online Library
Palytoxin (PTX) is a potent marine toxin that causies serious damage to various tissues and
organs. It has been reported to affect the transport of cations across the plasma membranes …
organs. It has been reported to affect the transport of cations across the plasma membranes …
Characterization of palytoxin-induced catecholamine secretion from cultured bovine adrenal chromaffin cells: Effects of Na+-and Ca2+-channel blockers
M Yoshizumi, A Nakanishi, H Houchi, K Morita… - Biochemical …, 1991 - Elsevier
The effect of palytoxin (PTX), a potent marine toxin, on catecholamine (CA) secretion from
cultured bovine adrenal chromaffin cells was examined. PTX at concentrations of over 10 …
cultured bovine adrenal chromaffin cells was examined. PTX at concentrations of over 10 …
Potential neurotoxins: Palytoxins
MT Fernández-Sánchez, D Cabrera-García… - Advances in …, 2021 - Elsevier
Palytoxin has been long associated to the ingestion of contaminated food in tropical coastal
areas. In the last years, however, the increasing number of reports of poisonings among …
areas. In the last years, however, the increasing number of reports of poisonings among …
Inhibition by ouabain of palytoxin-induced catecholamine secretion and calcium influx into cultured bovine adrenal chromaffin cells
M Yoshizumi, Y Ishimura, Y Masuda, H Houchi… - Biochemical …, 1994 - Elsevier
The effect of ouabain on palytoxin (PTX)-induced catecholamine secretion from cultured
bovine adrenal chromaffin cells was examined in relation to its effect on calcium (Ca 2+) …
bovine adrenal chromaffin cells was examined in relation to its effect on calcium (Ca 2+) …
Tetrodotoxin-insensitive Na+ channel activator palytoxin inhibits tyrosine uptake into cultured bovine adrenal chromaffin cells.
K Morita, K Teraoka, M Azuma, M Oka… - Molecular pharmacology, 1991 - ASPET
The effects of the tetrodotoxin-insensitive Na+ channel activator palytoxin on both the
secretion of endogenous catecholamines and the formation of 14C-catecholamines from …
secretion of endogenous catecholamines and the formation of 14C-catecholamines from …