Structure and function of β-1, 4-galactosyltransferase

PK Qasba, B Ramakrishnan… - Current drug …, 2008 - ingentaconnect.com
Beta-1, 4-galactosylransferase (β4Gal-T1) participates in the synthesis of Galβ1-4-GlcNAc-
disaccharide unit of glycoconjugates. It is a trans-Golgi glycosyltransferase (Glyco-T) with a …

What have we learned from glycosyltransferase knockouts in mice?

P Stanley - Journal of molecular biology, 2016 - Elsevier
There are five major classes of glycan including N-and O-glycans, glycosaminoglycans,
glycosphingolipids, and glycophosphatidylinositol anchors, all expressed at the molecular …

ABO blood group and related antigens, natural antibodies and transplantation

J Milland, MS Sandrin - Tissue antigens, 2006 - Wiley Online Library
The current success rate of transplant surgery and immunosuppression has led to a demand
for organs that has outstripped the supply. This has required investigation of alternate …

A novel missense mutation in the galactosyltransferase‐I (B4GALT7) gene in a family exhibiting facioskeletal anomalies and Ehlers–Danlos syndrome resembling the …

M Faiyaz‐Ul‐Haque, SHE Zaidi, M Al‐Ali… - American Journal of …, 2004 - Wiley Online Library
Abstract The Ehlers–Danlos syndrome (EDS) is a heterogeneous group of heritable
connective tissue disorders characterized by skin hyperextensibility, joint hypermobility, and …

Expression of genes encoding for proteins involved in heparan sulphate and chondroitin sulphate chain synthesis and modification in normal and malignant plasma …

C Bret, D Hose, T Reme, AC Sprynski… - British journal of …, 2009 - Wiley Online Library
Syndecan‐1 is a proteoglycan that concentrates heparin‐binding factors on the surface of
multiple myeloma cells, and probably plays a major role in multiple myeloma biology. As …

[HTML][HTML] β1, 4-galactosyltransferase v modulates breast cancer stem cells through wnt/β-catenin signaling pathway

BD Wei Tang, M Li, X Qi, J Li - Cancer Res Treat, 2020 - synapse.koreamed.org
Purpose Breast cancer stem cells (BCSCs) contribute to the initiation, development, and
recurrence of breast carcinomas. β1, 4-Galactosyltransferase V (B4GalT5), which catalyzes …

Structure and catalytic cycle of β-1, 4-galactosyltransferase

B Ramakrishnan, E Boeggeman, V Ramasamy… - Current opinion in …, 2004 - Elsevier
β-1, 4-galactosyltransferase-1, a housekeeping enzyme that functions in the synthesis of
glycoconjugates, has two flexible loops, one short and one long. Upon binding a metal ion …

B4GALT5 high expression associated with poor prognosis of hepatocellular carcinoma

Y Han, Z Li, Q Wu, H Liu, Z Sun, Y Wu, J Luo - BMC cancer, 2022 - Springer
Background B4GALT5 is postulated to be an important protein in sugar metabolism that
catalyzes the synthesis of lactosylceramide (LacCer). However, its role in hepatocellular …

Effect of a null mutation of the oviduct-specific glycoprotein gene on mouse fertilization

Y Araki, M Nohara, H Yoshida-Komiya… - Biochemical …, 2003 - portlandpress.com
The mammalian fertilization process takes place in a complex microenvironment within the
female genital tract. A member of the chitinase protein family, oviduct-specific glycoprotein …

A testis-specific regulator of complex and hybrid N-glycan synthesis

HH Huang, P Stanley - Journal of Cell Biology, 2010 - rupress.org
Database analyses identified 4933434I20Rik as a glycosyltransferase-like gene expressed
mainly in testicular germ cells and regulated during spermatogenesis. Expression of a …