Glioblastoma cell enrichment is critical for analysis of phosphorylated drug targets and proteomic–genomic correlations

C Mueller, AC deCarvalho, T Mikkelsen, NL Lehman… - Cancer research, 2014 - AACR
The quality of cancer genomic and proteomic data relies upon the quality of the clinical
specimens examined. Here, we show that data derived from non-microdissected …

18F-fluoromethylcholine (FCho), 18F-fluoroethyltyrosine (FET), and 18F-fluorodeoxyglucose (FDG) for the discrimination between high-grade glioma and radiation …

J Bolcaen, B Descamps, K Deblaere… - Nuclear medicine and …, 2015 - Elsevier
Introduction Discrimination between (high-grade) brain tumor recurrence and radiation
necrosis (RN) remains a diagnostic challenge because both entities have similar imaging …

Can artificial intelligence overtake human intelligence on the bumpy road towards glioma therapy?

PS Daisy, TS Anitha - Medical Oncology, 2021 - Springer
Gliomas are one of the most devastating primary brain tumors which impose significant
management challenges to the clinicians. The aggressive behaviour of gliomas is mainly …

Farewell to GBM-O: Genomic and transcriptomic profiling of glioblastoma with oligodendroglioma component reveals distinct molecular subgroups

BH Hinrichs, S Newman, CL Appin, W Dunn… - Acta neuropathologica …, 2016 - Springer
Introduction Glioblastoma with oligodendroglioma component (GBM-O) was recognized as a
histologic pattern of glioblastoma (GBM) by the World Health Organization (WHO) in 2007 …

Glioblastoma: biology, genetics, and behavior

DJ Brat - American Society of Clinical Oncology Educational …, 2012 - ascopubs.org
Overview: Glioblastoma (GBM) is a highly malignant, rapidly progressive astrocytoma that is
distinguished pathologically from lower-grade tumors by necrosis and microvascular …

Management of newly diagnosed glioblastoma: guidelines development, value and application

JJ Olson, CE Fadul, DJ Brat, S Mukundan… - Journal of neuro …, 2009 - Springer
The movement to create guidelines for management of medical maladies has been gaining
strength for quality, academic, financial and political purposes over the past two decades …

The role of neuropathology in the management of newly diagnosed glioblastoma: a systematic review and evidence-based clinical practice guideline

JE Velázquez Vega, DJ Brat, TC Ryken… - Journal of Neuro …, 2020 - Springer
Abstract Target Population These recommendations apply to adult patients with newly
diagnosed or suspected glioblastoma (GBM) Question For adult patients with newly …

Nanotechnology applications for glioblastoma

EK Nduom, A Bouras, M Kaluzova… - Neurosurgery Clinics of …, 2012 - Elsevier
Glioblastoma remains one of the most difficult cancers to treat and represents the most
common primary malignancy of the brain. Although conventional treatments have found …

MALDI imaging and in‐source decay for top‐down characterization of glioblastoma

R Ait‐Belkacem, C Berenguer, C Villard, LH Ouafik… - …, 2014 - Wiley Online Library
Glioblastoma multiforme is one of the most common intracranial tumors encountered in
adults. This tumor of very poor prognosis is associated with a median survival rate of …

Pharmacokinetic studies of 68Ga-labeled Bombesin (68Ga-BZH3) and F-18 FDG PET in patients with recurrent gliomas and comparison to grading: preliminary …

A Dimitrakopoulou-Strauss, M Seiz… - Clinical nuclear …, 2011 - journals.lww.com
Purpose: Dynamic PET studies with a 68 Ga-Bombesin analog, the 68 Ga-BZH 3, were
performed in patients with highly suspected recurrent gliomas to investigate the effect of the …