Cells are constantly exposed to a large variety of lipids. Traditionally, these molecules were
thought to serve as simple energy storing molecules. More recently it has been realized that …

NADPH oxidases (Nox) represent a family of hetero-oligomeric enzymes whose exclusive
biological function is the generation of reactive oxygen species (ROS). Nox-derived ROS are …

Peroxisome proliferator-activated receptors (PPARs) are ligand-activated nuclear
transcription factors that belong to the nuclear receptor superfamily. Three isoforms of PPAR …

Patients with well-controlled low-density lipoprotein cholesterol levels, but persistent high
triglycerides, remain at increased risk for cardiovascular events as evidenced by multiple …

Atherosclerosis is a chronic inflammatory disease with deposition of excessive cholesterol in
the arterial intima. Peroxisome proliferator-activated receptor α (PPARα) is a nuclear …

Objective—Peroxisome proliferator–activated receptor-α (PPARα) is a ligand-activated
transcription factor that controls lipid metabolism and inflammation. PPARα is activated by …

OBJECTIVE—To investigate the effects of fenofibrate and coenzyme Q10 (CoQ) on diastolic
function, ambulatory blood pressure (ABP), and heart rate (HR) in type 2 diabetic subjects …

Doxorubicin (DOX), a chemotherapeutic drug widely used in the clinical setting, is known to
cause serious cardiotoxicity and greatly reduces the survival rate as well as quality of life of …

The peroxisome proliferator‐activated receptors, PPAR α, PPAR β/δ and PPAR γ, are ligand‐
activated transcriptional factors belonging to the nuclear receptors superfamily and they are …

Recent research has revealed roles for the peroxisome proliferator activated receptor
(PPAR) family of transcription factors in blood pressure regulation, expanding the possible …