The conjugation of biomolecules can impart materials with the bioactivity necessary to
modulate specific cell behaviors. While the biological roles of particular polypeptide …

Biomass has emerged as a potential alternative feedstock to dwindling fossil fuel reserves.
Starting in the 1990s, extensive research has been directed towards the synthesis of useful …

Natural flavonoids, especially in their glycosylated forms, are the most abundant phenolic
compounds found in plants, fruit, and vegetables. They exhibit a large variety of beneficial …

The application of small molecules as catalysts for the diversification of natural product
scaffolds is reviewed. Specifically, principles that relate to the selectivity challenges intrinsic …

The interactions of cell surface carbohydrates as well as of soluble glycoconjugates with
their receptor proteins rule fundamental processes in cell biology. One of the …

Glycosylation is a chemical transformation that is centrally important in all glycoscience and
related technologies. Catalysts offering good control over reactivity and selectivity in …

It has been amply constated that sugar ligand multivalency increases lectin-binding avidities
dramatically, thereby modulating the capacity of carbohydrates to participate in …

Recognition of glycans by proteins plays a crucial role in a variety of physiological
processes in cells and living organisms. In addition, interactions of glycans with proteins are …

Cellular communication events are mediated by interactions between cell-surface sugars
and lectins, which are carbohydrate-binding proteins. Galectins are β-galactosyl-binding …

In this review we highlight the potential for biomedical applications of dendritic
glycopolymers based on polyamine scaffolds. The complex interplay of the molecular …