Background To date, standardising clinical predictive biomarkers for assessing the response
to immunotherapy remains challenging due to variations in personal genetic signatures …

Circular RNAs (circRNAs) are single-stranded, covalently closed RNA molecules formed by
mRNA exon back-splicing. Although the circRNA functions remain largely unknown, their …

Lung cancer is the leading cause of cancer-related mortality worldwide. A major contributing
factor to the poor survival rates in lung cancer is the high prevalence of metastasis at the …

Current treatment strategies for cancer, especially advanced cancer, are limited and
unsatisfactory. One of the most substantial advances in cancer therapy, in the last decades …

Lung cancer holds the highest mortality rate among malignancies worldwide. Nevertheless,
the potential molecular mechanisms of its tumorigenesis and evolution remain obscure …

ABSTRACT Circular RNAs (CircRNAs) are reported to exert vital regulatory roles in the
occurrence and development of various human malignancies, including non-small cell lung …

Objective Co‐occurring anti‐tripartite motif‐containing protein 9 and 67 autoantibodies
(TRIM9/67‐IgG) have been reported in only a very few cases of paraneoplastic cerebellar …

Immune checkpoint inhibitors targeting the programmed cell death protein 1 (PD‑
1)/programmed death ligand 1 (PD‑L1) axis have achieved marked and durable efficacy in …

Cancer is a major threat to human health and longevity. Chemotherapy is an effective
approach to inhibit cancer cell proliferation, but a growing number of cancer patients are …

Circular RNAs (circRNAs) are non-coding single-stranded covalently closed circular RNA,
mainly produced by reverse splicing of exons of precursor mRNAs (pre-mRNAs). The …