PURPOSE: Depressive symptomatology is frequently associated with interleukin (IL)-2 and
interferon alfa-2b (INFα-2b) therapy in cancer patients. The objective of the present study …

CONTEXT: Metastatic renal cell carcinoma (mRCC) has long been treated only by
immunotherapy with good results only in a small population of patients. In recent years …

Renal cell carcinoma (RCC) are frequently chemo-and radiation resistant. Thus, there is a
need for identifying biological features of these cells that could serve as alternative …

The development of specific angiogenesis inhibitors has drastically improved renal cancer
treatment in recent years. Currently, four VEGF receptor inhibitors (sorafenib, sunitinib …

Objective: Therapeutic decision-making in metastatic renal cell carcinoma (MRCC) is based
on conventional radiological evaluation. Fluorodeoxyglucose positron emission tomography …

This paper is an overview on the place of IFN-α in metastatic renal cell carcinoma (MRCC).
After a presentation of MRCC and the mode of action of IFN-α, the results of studies …

Рассмотрены эффективность и переносимость Темсиролимуса у пациентов с
метастатическим раком почки. Отмечены высокая противоопухолевая активность и …

The epidermal growth factor receptor (EGFR) pathway is a very well-known pathway
implicated in proliferation, growth and metastatic development of various tumor types …

Recently, epitope prediction software for HLA-DR binding sequences has become available.
In view of the importance of T helper (Th) cell activation in immunotherapy of cancer and …

To isolate the over-expressed genes in human renal cell carcinoma (RCC) and analyze its
molecular basis of carcinogenesis, we used the mRNA from human RCC tissues as tester …