Mitochondrial biogenesis is a complex process. It requires the contribution of both the
nuclear and the mitochondrial genomes and therefore cross talk between the nucleus and …

Mitochondria are key organelles for cellular homeostasis. They generate the most part of
ATP that is used by cells through oxidative phosphorylation. They also produce reactive …

Abstract In plants, 3´, 5´-cyclic adenosine monophosphate (cAMP) is an important second
messenger with varied functions; however, only a few adenylyl cyclases (ACs) that …

Electrophysiological and structural disruptions in cardiac arrhythmias are closely related to
mitochondrial dysfunction. Mitochondria are an organelle generating ATP, thereby satisfying …

G-protein coupled receptor (GPCR) kinases (GRKs) and β-arrestins play key roles in GPCR
and non-GPCR cellular responses. In fact, GRKs and arrestins are involved in a plethora of …

Abstract Nitroxyl (HNO), one-electron reduced and protonated sibling of nitric oxide (NO), is
a potential regulator of cardiovascular functions. It produces positive inotropic, lusitropic …

Asprosin is a newly discovered adipokine that is involved in regulating metabolism.
Sympathetic overactivity contributes to the pathogenesis of several cardiovascular diseases …

Abstract β-Adrenergic receptor (β-AR) overactivation is a major pathological factor
associated with cardiac diseases and mediates cardiac inflammatory injury. Glibenclamide …

Activation of the renin‐angiotensin system (RAS) contributes to the pathogenesis of
cardiovascular diseases. Sodium potassium ATPase (NKA) expression and activity are often …

The treatment of pediatric heart failure is a long-standing unmet medical need. Angiotensin II
supports mammalian perinatal circulation by activating cardiac L-type Ca2+ channels …