C-type lectins (CTLs) represent the most complex family of animal/human lectins that
comprises 17 different groups. During evolution, CTLs have developed by diversification to …

Sialylated N-glycans play essential roles in the immune system, pathogen recognition and
cancer. This review approaches the sialylation of N-glycans from three perspectives. The …

An experimental observation on se lectin g binding partners underlies the introduction of the
term 'lectin'. Agglutination of erythrocytes depending on their blood-group status revealed …

Carbohydrates have physiological importance far beyond their roles as source of energy
(glycolysis) and activated hydrogen for synthesis (pentosephosphate pathway) or as …

One route of realizing the information of glycans involves endogenous receptors (lectins).
Occurrence at branch ends renders galactosides particularly accessible. Thus, they are …

The cell surface is the platform for presentation of biochemical signals that are required for
intercellular communication. Their profile necessarily needs to be responsive to internal and …

Proteins undergo co-and posttranslational modifications, and their glycosylation is the most
frequent and structurally variegated type. Histochemically, the detection of glycan presence …

A code is defined by the nature of the symbols, which are used to generate information‐
storing combinations (eg oligo‐and polymers). Like nucleic acids and proteins, oligo‐and …

Having identified glycans of cellular glycoconjugates as versatile molecular messages, their
recognition by sugar receptors (lectins) is a fundamental mechanism within the flow of …

Precise translation of glycan-encoded information into cellular activity depends critically on
highly specific functional pairing between glycans and their human lectin counter receptors …