Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training

B Egan, AP Sharples - Physiological Reviews, 2023 - journals.physiology.org
Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

Resistance exercise as a treatment for sarcopenia: prescription and delivery

C Hurst, SM Robinson, MD Witham, RM Dodds… - Age and …, 2022 - academic.oup.com
Sarcopenia is a generalised skeletal muscle disorder characterised by reduced muscle
strength and mass and associated with a range of negative health outcomes. Currently …

Role of inactivity in chronic diseases: evolutionary insight and pathophysiological mechanisms

FW Booth, CK Roberts, JP Thyfault… - Physiological …, 2017 - journals.physiology.org
This review proposes that physical inactivity could be considered a behavior selected by
evolution for resting, and also selected to be reinforcing in life-threatening situations in …

Exercise adaptations: molecular mechanisms and potential targets for therapeutic benefit

SL McGee, M Hargreaves - Nature Reviews Endocrinology, 2020 - nature.com
Exercise is fundamental for good health, whereas physical inactivity underpins many chronic
diseases of modern society. It is well appreciated that regular exercise improves metabolism …

Oxidative stress in type 2 diabetes: impacts from pathogenesis to lifestyle modifications

A Caturano, M D'Angelo, A Mormone, V Russo… - Current Issues in …, 2023 - mdpi.com
Oxidative stress is a critical factor in the pathogenesis and progression of diabetes and its
associated complications. The imbalance between reactive oxygen species (ROS) …

The general adaptation syndrome: a foundation for the concept of periodization

AJ Cunanan, BH DeWeese, JP Wagle, KM Carroll… - Sports Medicine, 2018 - Springer
Recent reviews have attempted to refute the efficacy of applying Selye's general adaptation
syndrome (GAS) as a conceptual framework for the training process. Furthermore, the …

[HTML][HTML] The molecular athlete: exercise physiology from mechanisms to medals

R Furrer, JA Hawley, C Handschin - Physiological reviews, 2023 - journals.physiology.org
Human skeletal muscle demonstrates remarkable plasticity, adapting to numerous external
stimuli including the habitual level of contractile loading. Accordingly, muscle function and …

[HTML][HTML] Compatibility of concurrent aerobic and strength training for skeletal muscle size and function: an updated systematic review and meta-analysis

M Schumann, JF Feuerbacher, M Sünkeler, N Freitag… - Sports medicine, 2022 - Springer
Background Both athletes and recreational exercisers often perform relatively high volumes
of aerobic and strength training simultaneously. However, the compatibility of these two …

Periodization and block periodization in sports: emphasis on strength-power training—a provocative and challenging narrative

MH Stone, WG Hornsby, GG Haff, AC Fry… - The Journal of …, 2021 - journals.lww.com
Abstract Stone, MH, Hornsby, WG, Haff, GG, Fry, AC, Suarez, DG, Liu, J, Gonzalez-Rave, JM,
and Pierce, KC. Periodization and block periodization in sports: emphasis on strength-power …

The role of AMPK in the regulation of skeletal muscle size, hypertrophy, and regeneration

DM Thomson - International journal of molecular sciences, 2018 - mdpi.com
AMPK (5'-adenosine monophosphate-activated protein kinase) is heavily involved in
skeletal muscle metabolic control through its regulation of many downstream targets …