Multicomponent reactions and photo/electrochemistry join forces: atom economy meets energy efficiency

GA Coppola, S Pillitteri, EV Van der Eycken… - Chemical Society …, 2022 - pubs.rsc.org
Visible-light photoredox catalysis has been regarded as an extremely powerful tool in
organic chemistry, bringing the spotlight back to radical processes. The versatility of …

Catalytic three-component dicarbofunctionalization reactions involving radical capture by nickel

S Zhu, X Zhao, H Li, L Chu - Chemical Society Reviews, 2021 - pubs.rsc.org
The catalytic dicarbofunctionalization of unsaturated π bonds represents a powerful platform
for the rapid construction of complex motifs. Despite remarkable progress, novel and efficient …

[HTML][HTML] Piperidine derivatives: recent advances in synthesis and pharmacological applications

NA Frolov, AN Vereshchagin - International Journal of Molecular Sciences, 2023 - mdpi.com
Piperidines are among the most important synthetic fragments for designing drugs and play
a significant role in the pharmaceutical industry. Their derivatives are present in more than …

Cu and Cu-based nanoparticles: synthesis and applications in catalysis

MB Gawande, A Goswami, FX Felpin, T Asefa… - Chemical …, 2016 - ACS Publications
The applications of copper (Cu) and Cu-based nanoparticles, which are based on the earth-
abundant and inexpensive copper metal, have generated a great deal of interest in recent …

Consecutive multicomponent reactions for the synthesis of complex molecules

S Zhi, X Ma, W Zhang - Organic & Biomolecular Chemistry, 2019 - pubs.rsc.org
Multicomponent reactions (MCRs) involving a minimum of three reactants or reaction
centers are conducted in one pot and with a single operational step. This synthetic method …

Multicomponent reaction toolbox for peptide macrocyclization and stapling

L Reguera, DG Rivera - Chemical reviews, 2019 - ACS Publications
In the past decade, multicomponent reactions have experienced a renaissance as powerful
peptide macrocyclization tools enabling the rapid creation of skeletal complexity and …

Constructing robust covalent organic frameworks via multicomponent reactions

PL Wang, SY Ding, ZC Zhang, ZP Wang… - Journal of the …, 2019 - ACS Publications
Methodology development of robust linkages is fundamentally important for the synthesis
and application of covalent organic frameworks (COFs). We report herein a new strategy …

Multicomponent reactions: advanced tools for sustainable organic synthesis

RC Cioc, E Ruijter, RVA Orru - Green Chemistry, 2014 - pubs.rsc.org
Sustainable or green chemistry has established firm ground providing essential design
criteria for the development of efficient chemical syntheses of complex, high added value …

Aerobic copper-catalyzed organic reactions

SE Allen, RR Walvoord, R Padilla-Salinas… - Chemical …, 2013 - ACS Publications
The chemistry of copper is extremely rich because it can easily access Cu0, CuI, CuII, and
CuIII oxidation states allowing it to act through one-electron or two-electron processes. As a …

[HTML][HTML] Two decades of recent advances of Ugi reactions: synthetic and pharmaceutical applications

MA Fouad, H Abdel-Hamid, MS Ayoup - RSC advances, 2020 - pubs.rsc.org
Multicomponent reactions (MCRs) are powerful synthetic tools in which more than two
starting materials couple with each other to form multi-functionalized compounds in a one …