A review of current trends with type 2 diabetes epidemiology, aetiology, pathogenesis, treatments and future perspectives

J Reed, S Bain, V Kanamarlapudi - Diabetes, Metabolic Syndrome …, 2021 - Taylor & Francis
Abstract Type 2 diabetes (T2D), which has currently become a global pandemic, is a
metabolic disease largely characterised by impaired insulin secretion and action. Significant …

Chronic adipose tissue inflammation linking obesity to insulin resistance and type 2 diabetes

F Zatterale, M Longo, J Naderi, GA Raciti… - Frontiers in …, 2020 - frontiersin.org
Obesity is one of the major health burdens of the 21st century as it contributes to the growing
prevalence of its related comorbidities, including insulin resistance and type 2 diabetes …

[HTML][HTML] The potential impacts of obesity on COVID-19

AAD Albashir - Clinical medicine, 2020 - Elsevier
Obese patients are at increased risk of exacerbations from viral respiratory infections. During
the H1N1 pandemic, obesity was associated with an increased risk of influenza-associated …

Sociodemographic and lifestyle-related risk factors for identifying vulnerable groups for type 2 diabetes: a narrative review with emphasis on data from Europe

I Kyrou, C Tsigos, C Mavrogianni, G Cardon… - BMC endocrine …, 2020 - Springer
Background Type 2 diabetes mellitus (T2DM) comprises the vast majority of all diabetes
cases in adults, with alarmingly increasing prevalence over the past few decades worldwide …

Implicating the effect of ketogenic diet as a preventive measure to obesity and diabetes mellitus

S Kumar, T Behl, M Sachdeva, A Sehgal, S Kumari… - Life sciences, 2021 - Elsevier
Obesity and diabetes are the two major metabolic complications linked with bad eating
habits and the sedentary (lazy) lifestyle. In the worst-case situation, metabolic problems are …

Polycystic ovary syndrome (PCOS) and COVID-19: an overlooked female patient population at potentially higher risk during the COVID-19 pandemic

I Kyrou, E Karteris, T Robbins, K Chatha, F Drenos… - BMC medicine, 2020 - Springer
Background In women of reproductive age, polycystic ovary syndrome (PCOS) constitutes
the most frequent endocrine disorder. Women with PCOS are considered to typically belong …

The related metabolic diseases and treatments of obesity

M Yang, S Liu, C Zhang - Healthcare, 2022 - mdpi.com
Obesity is a chronic disease characterized by the abnormal or excessive accumulation of
body fat, affecting more than 1 billion people worldwide. Obesity is commonly associated …

Fibroblast growth factor–based pharmacotherapies for the treatment of obesity-related metabolic complications

L Jin, R Yang, L Geng, A Xu - Annual Review of Pharmacology …, 2023 - annualreviews.org
The fibroblast growth factor (FGF) family, which comprises 22 structurally related proteins,
plays diverse roles in cell proliferation, differentiation, development, and metabolism. Among …

Obesity and breast cancer: a case of inflamed adipose tissue

R Kolb, W Zhang - Cancers, 2020 - mdpi.com
Obesity is associated with an increased risk of estrogen receptor-positive breast cancer in
postmenopausal women and a worse prognosis for all major breast cancer subtypes …

[HTML][HTML] Obesity and dyslipidemia

KR Feingold - 2015 - europepmc.org
Abnormalities in lipid metabolism are very commonly observed in patients who are obese.
Approximately 60-70% of patients with obesity are dyslipidemic. The lipid abnormalities in …