Cancer cachexia: molecular mechanisms and treatment strategies
T Setiawan, IN Sari, YT Wijaya, NM Julianto… - Journal of Hematology & …, 2023 - Springer
Muscle wasting is a consequence of physiological changes or a pathology characterized by
increased catabolic activity that leads to progressive loss of skeletal muscle mass and …
increased catabolic activity that leads to progressive loss of skeletal muscle mass and …
Cardio-onco-metabolism: metabolic remodelling in cardiovascular disease and cancer
Cardiovascular disease and cancer are the two leading causes of morbidity and mortality in
the world. The emerging field of cardio-oncology has revealed that these seemingly …
the world. The emerging field of cardio-oncology has revealed that these seemingly …
Therapeutic influence on important targets associated with chronic inflammation and oxidative stress in cancer treatment
M Neganova, J Liu, Y Aleksandrova, S Klochkov, R Fan - Cancers, 2021 - mdpi.com
Simple Summary There is no doubt that the need for new effective methods of cancer
treatment remains challenging, as cancer is the second cause of death based on the …
treatment remains challenging, as cancer is the second cause of death based on the …
A new classification of cardio-oncology syndromes
RA de Boer, JP Aboumsallem, V Bracun, D Leedy… - Cardio-oncology, 2021 - Springer
Increasing evidence suggests a multifaceted relationship exists between cancer and
cardiovascular disease (CVD). Here, we introduce a 5-tier classification system to categorize …
cardiovascular disease (CVD). Here, we introduce a 5-tier classification system to categorize …
Targeting cancer cachexia: Molecular mechanisms and clinical study
Cancer cachexia is a complex systemic catabolism syndrome characterized by muscle
wasting. It affects multiple distant organs and their crosstalk with cancer constitute cancer …
wasting. It affects multiple distant organs and their crosstalk with cancer constitute cancer …
Vascular impact of cancer therapies: the case of BTK (Bruton tyrosine kinase) inhibitors
Novel targeted cancer therapies have revolutionized oncology therapies, but these
treatments can have cardiovascular complications, which include heterogeneous cardiac …
treatments can have cardiovascular complications, which include heterogeneous cardiac …
Cardiac dysfunction promotes cancer progression via multiple secreted factors
L Awwad, A Aronheim - Cancer research, 2022 - AACR
Heart failure and cancer are the leading cause of deaths worldwide. While heart failure and
cancer have been considered separate diseases, it is becoming evident that they are highly …
cancer have been considered separate diseases, it is becoming evident that they are highly …
Recent advances in pluripotent stem cell-derived cardiac organoids and heart-on-chip applications for studying anti-cancer drug-induced cardiotoxicity
Cardiovascular disease (CVD) caused by anti-cancer drug-induced cardiotoxicity is now the
second leading cause of mortality among cancer survivors. It is necessary to establish …
second leading cause of mortality among cancer survivors. It is necessary to establish …
Association between insulin resistance and cardiac remodeling in HER2-positive breast cancer patients: a real-world study
Y Shi, Z Qiu, J Yu, Z Li, S Hua, Y Chen, X Chen, K Shen… - BMC cancer, 2023 - Springer
Background Insulin resistance is an overlapping risk factor for both heart and breast cancer,
while its interaction with cardiotoxicity in breast cancer (BC) patients is not clear. This study …
while its interaction with cardiotoxicity in breast cancer (BC) patients is not clear. This study …
Cardiac radiation improves ventricular function in mice and humans with cardiomyopathy
Background Rapidly dividing cells are more sensitive to radiation therapy (RT) than
quiescent cells. In the failing myocardium, macrophages and fibroblasts mediate collateral …
quiescent cells. In the failing myocardium, macrophages and fibroblasts mediate collateral …