Osteoporosis is a widespread systemic disease characterized by a decrease in bone mass
and an imbalance of the microarchitecture of bone tissue. Experimental and clinical studies …

Osteoporosis is a multifactorial disease influenced by genetic and environmental factors,
which contributes to an increased risk of bone fracture, but early diagnosis of this disease …

Most replicated genetic determinants for type 1 diabetes are common (minor allele
frequency [MAF]> 5%). We aimed to identify novel rare or low-frequency (MAF< 5%) single …

Hip fracture is the clinically most important fracture, but the genetic architecture of hip
fracture is unclear. Here, we perform a large-scale hip fracture genome-wide association …

Genomic technologies have evolved rapidly contributing to the understanding of diseases.
Genome-wide association studies (GWAS) and whole-exome sequencing have aided the …

Non syndromic orofacial clefts specifically non-syndromic cleft lip/palate are one of the most
common craniofacial malformation among birth defects in human having multifactorial …

Introduction Maternal vitamin D status in pregnancy has been linked to many health
outcomes in mother and offspring. A wealth of observational studies have reported on both …

Aims Genome-wide association studies (GWASs) have discovered hundreds of common
genetic variants for atherosclerotic disease and cardiovascular risk factors. The translation of …

Osteoporosis predisposes patients to spinal fragility fractures. Imaging plays a key role in the
diagnosis and prognostication of these osteoporotic vertebral fractures (OVF). However, the …

Nonsyndromic cleft lip with or without cleft palate (nsCL/P) is among the most common
human birth defects with multifactorial etiology. Here, we present results from a genome …