Betulin, a pentacyclic triterpene and a plant pentacyclic triterpene metabolite, can be found
in large quantities in the outer bark of the birches (Betula, Betulaceae). Betulinic acid …

Saponins are widely distributed plant natural products with vast structural and functional
diversity. They are typically composed of a hydrophobic aglycone, which is extensively …

Terpenoids are the largest class of natural products, most of which are derived from plants.
Amongst their numerous biological properties, their anti-tumor effects are of interest for they …

Along more than a decade, R&D on supercritical fluid extraction (SFE) of vegetable matrices
has been increasingly reported in the literature. Aiming at portraying the current state of this …

Ursolic acid (UA) is a natural terpene compound exhibiting many pharmaceutical properties.
In this review the current state of knowledge about the health-promoting properties of this …

Fruit-derived bioactive substances have been spotlighted as a regulator against various
diseases due to their fewer side effects compared to chemical drugs. Among the most …

Ursolic and oleanolic acids are secondary plant metabolites that are known to be involved in
the plant defence system against water loss and pathogens. Nowadays these triterpenoids …

Oleanolic acid (3β-hydroxyolean-12-en-28-oic acid) is a pentacyclic triterpenoid compound
with a widespread occurrence throughout the plant kingdom. In nature, the compound exists …

Diabetes mellitus is a chronic metabolic disease which is a serious global problem. In 2010
an estimated 285 million people had diabetes and within the next 20 years this value is …

Breast cancer remains a major cause of death in the United States as well as the rest of the
world. In view of the limited treatment options for patients with advanced breast cancer …