Betulinic acid as apoptosis activator: Molecular mechanisms, mathematical modeling and chemical modifications
A natural product betulinic acid (BA) has gained a huge significance in the recent years for
its strong cytotoxicity. Surprisingly, in spite of being an interesting cancer protecting agent on …
its strong cytotoxicity. Surprisingly, in spite of being an interesting cancer protecting agent on …
[HTML][HTML] Immunomodulatory effects and structure-activity relationship of botanical pentacyclic triterpenes: A review
Botanical pentacyclic triterpenes possessed a broad range of pharmacological activities
such as anti-oxidant, anti-tumor, anti-microbial and anti-inflammatory activities. It is believed …
such as anti-oxidant, anti-tumor, anti-microbial and anti-inflammatory activities. It is believed …
[HTML][HTML] In vitro evaluation of anticancer potentials of lupeol isolated from Elephantopus scaber L. on MCF-7 cell line
D Pitchai, A Roy, C Ignatius - Journal of advanced pharmaceutical …, 2014 - journals.lww.com
Lupeol is a triterpenoid, present in most of the medicinally effective plants and possess a
wide range of biological activity against human diseases. The present study aims at …
wide range of biological activity against human diseases. The present study aims at …
High value triterpenic compounds from the outer barks of several Eucalyptus species cultivated in Brazil and in Portugal
RMA Domingues, GDA Sousa, CM Silva… - Industrial Crops and …, 2011 - Elsevier
The chemical composition of the lipophilic extracts of the inner and outer bark fractions of
Eucalyptus grandis and Eucalyptus urograndis (E. grandis× Eucalyptus urophylla) cultivated …
Eucalyptus grandis and Eucalyptus urograndis (E. grandis× Eucalyptus urophylla) cultivated …
[HTML][HTML] The wound healing properties of betulin from birch bark from bench to bedside
A Scheffler - Planta medica, 2019 - thieme-connect.com
With central European approval in January 2016 for a betulin-oleogel (Episalvan), used to
accelerate wound closure in partial thickness wounds, the herbal active ingredient triterpene …
accelerate wound closure in partial thickness wounds, the herbal active ingredient triterpene …
A bioguided identification of the active compounds that contribute to the antiproliferative/cytotoxic effects of rosemary extract on colon cancer cells
I Borrás-Linares, A Pérez-Sánchez… - Food and Chemical …, 2015 - Elsevier
Rosemary extracts have exhibited potential cytostatic or cytotoxic effects in several cancer
cell models but their bioactive compounds are yet to be discovered. In this work, the …
cell models but their bioactive compounds are yet to be discovered. In this work, the …
[HTML][HTML] EGFR-targeted pentacyclic triterpene analogues for glioma therapy
Glioma, particularly its most malignant form, glioblastoma multiforme (GBM), is the most
common and aggressive malignant central nervous system tumor. The drawbacks of the …
common and aggressive malignant central nervous system tumor. The drawbacks of the …
[HTML][HTML] Application of UHPLC-ESI-QTOF-MS in phytochemical profiling of sage (Salvia officinalis) and rosemary (Rosmarinus officinalis)
R Velamuri, Y Sharma, J Fagan… - Planta Medica …, 2020 - thieme-connect.com
UHPLC with QTOF-MS is widely used as a powerful tool for metabolomic analysis. This
technology has recently been applied to the analysis of polyphenols in food and herb …
technology has recently been applied to the analysis of polyphenols in food and herb …
Anti-angiogenic and anti-cancer evaluation of betulin nanoemulsion in chicken chorioallantoic membrane and skin carcinoma in Balb/c mice
CA Dehelean, S Feflea, D Gheorgheosu… - Journal of …, 2013 - ingentaconnect.com
Betulin (Bet), the main component of birch tree bark, has been recently reported to exert
anticancer activity in several cell lines; however the underlying mechanisms are only …
anticancer activity in several cell lines; however the underlying mechanisms are only …
Biosynthesis of structurally diverse triterpenes in plants: the role of oxidosqualene cyclases
S Ghosh - 2016 - insajournal.in
Triterpenes, thirty-carbon compounds derived from five-carbon isoprene units, are among
the largest and diverse classes of natural products. To date, over 20,000 distinct triterpene …
the largest and diverse classes of natural products. To date, over 20,000 distinct triterpene …