AlphaFold2 (AF2) and RoseTTaFold (RF) have revolutionized structural biology, serving as
highly reliable and effective methods for predicting protein structures. This article explores …

Investigating protein–protein interactions is crucial for understanding cellular biological
processes because proteins often function within molecular complexes rather than in …

Recombinant proteins play pivotal roles in numerous applications including industrial
biocatalysts or therapeutics. Despite the recent progress in computational protein structure …

In CASP15, 87 predictors submitted around 11 000 models on 41 assembly targets. The
community demonstrated exceptional performance in overall fold and interface contact …

We present the results for CAPRI Round 54, the 5th joint CASP‐CAPRI protein assembly
prediction challenge. The Round offered 37 targets, including 14 homodimers, 3 homo …

Accurate protein structure prediction using computational methods remains a challenge in
molecular biology. Recent advances in AI-powered algorithms provide a transformative …

Protein interactions are essential for cellular processes. In recent years there has been
significant progress in computational prediction of 3D structures of individual protein chains …

Post-translational modifications (PTMs) of transcription factors regulate transcriptional
activity and play a key role in essentially all biological processes and generate …

Protein aggregation is a hallmark of multiple neurodegenerative diseases and a great
hindrance in recombinant protein production, handling, and storage. Identification of …

Many biomedical applications, such as classification of binding specificities or
bioengineering, depend on the accurate definition of protein binding interfaces. Depending …