TLR7: A new sensor of viral infection

K Crozat, B Beutler - … of the national academy of sciences, 2004 - National Acad Sciences
The preponderance of mammalian resistance to infection is inher-ited rather than acquired.
Even without lymphoid cells, mammals still protect themselves. They respond violently to …

Vaccines as treatments for prostate cancer

I Rastogi, A Muralidhar, DG McNeel - Nature Reviews Urology, 2023 - nature.com
Prostate cancer is a leading cause of death in men worldwide. For over 30 years, growing
interest has focused on the development of vaccines as treatments for prostate cancer, with …

The present and future of biomarkers in prostate cancer: proteomics, genomics, and immunology advancements: supplementary issue: biomarkers and their essential …

PO Gaudreau, J Stagg, D Soulières… - Biomarkers in …, 2016 - journals.sagepub.com
Prostate cancer (PC) is the second most common form of cancer in men worldwide.
Biomarkers have emerged as essential tools for treatment and assessment since the …

Modified polynucleotides encoding basic helix-loop-helix family member E41

T Chakraborty, A De Fougerolles - US Patent 9,107,886, 2015 - Google Patents
2014-03-03 Assigned to MODERNA THERAPEUTICS, INC. reassignment MODERNA
THERAPEUTICS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …

Modified polynucleotides encoding copper metabolism (MURR1) domain containing 1

T Chakraborty, A De Fougerolles - US Patent 9,095,552, 2015 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
49235350&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Modified polynucleotides encoding citeD4

T Chakraborty, A De Fougerolles - US Patent 9,114,113, 2015 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
49235350&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Modified polynucleotides for the production of G-CSF

A De Fougerolles, KM Wood, SM Elbashir… - US Patent …, 2014 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
48610363&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Modified polynucleotides encoding aquaporin-5

T Chakraborty, A De Fougerolles - US Patent 9,220,792, 2015 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
49235350&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Split dose administration

A De Fougerolles, SM Elbashir - US Patent 9,186,372, 2015 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
48610363&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Cancer immunotherapy using RNA-loaded dendritic cells

P Ponsaerts, VFI Van Tendeloo… - Clinical & Experimental …, 2003 - academic.oup.com
Dendritic cells (DC) are the most professional antigen-presenting cells of the immune
system and are capable of initiating immune responses in vitro and in vivo. One of the great …