Ethnopharmacological relevance Depression, one of the most common psychiatric
disorders, is the fourth leading cause of long-term disability worldwide. A series of causes …

Psychotropic effect of Crocus sativus L.(family Iridaceae) biologically active chemical
compounds are quite well documented and they can therefore be used in addition to the …

Post-stroke depression (PSD) is a common complication and associates with poor physical
recovery, low quality of life and high mortality after cerebral infarction. However, the …

Objective Chaihu Shugan San (CSS) is a common antidepressant prescription in traditional
Chinese medicines. However, its active ingredients and mechanisms are unknown. The aim …

Abstract The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2), first broke out in Wuhan, China, in 2019. SARS …

The neuroimmune and neuroendocrine systems are two critical biological systems in the
pathogenesis of depression. Clinical and preclinical studies have demonstrated that the …

Mental health problems can be physically, emotionally and economically demanding,
impacting patients, families, friends and society. Complementary techniques can help open …

Objectives: Major depressive disorder (MDD) has been reported to affect an increasing
number of individuals due to the modern lifestyle. Because of its complicated mechanisms …

The incidence of depression has been steadily rising in recent years, making it one of the
most prevalent mental illnesses. As the pursuit of novel antidepressant drugs captivates the …

Background: Current mainstream treatment of major depressive disorder (MDD) has a
disadvantage in delayed onset of efficacy, making detection of early signatures predicative …