[HTML][HTML] Searching for natural Aurora a kinase inhibitors from peppers using molecular docking and molecular dynamics

P Siudem, Ł Szeleszczuk, K Paradowska - Pharmaceuticals, 2023 - mdpi.com
Natural products are the precursors of many medicinal substances. Peppers (Piper,
Capsicum, Pimienta) are a rich source of compounds with potential multidirectional …

Structure-Activity Relationship Studies on VEGFR2 Tyrosine Kinase Inhibitors for Identification of Potential Natural Anticancer Compounds

M Verma, A Sarfraz, I Hasan, PG Vasudev… - Medicinal …, 2024 - ingentaconnect.com
Background: Over-expression of Vascular Endothelial Growth Factor Receptors (VEGFRs)
leads to the hyperactivation of oncogenes. For inhibition of this hyperactivation, the USA …

[HTML][HTML] Network-Derived Radioresistant Breast Cancer Target with Candidate Inhibitors from Brown Algae: A Sequential Assessment from Target Selection to …

M Sivakumar, SF Ahmad, TB Emran… - Marine Drugs, 2023 - mdpi.com
Despite significant progress in early detection and treatment, a few aggressive breast
cancers still exhibit resistance to therapy. This study aimed to identify a therapeutic target for …