OBJECTIVE: Elevated plasma total homocysteine (tHcy) concentrations are associated with
premature cardiovascular disease. We assessed tHcy, folate, vitamin B12 (Vit B12), vitamin …

Methionine synthase reductase (MTRR) is the locus of the cblE class of inborn errors of
cobalamin metabolism that is characterized by megaloblastic anemia and homocystinuria …

Patients with chronic kidney disease who are on dialysis or with a kidney transplant have
higher total plasma homocysteine concentrations than individuals who are free from kidney …

Objectives Human novel oxidoreductase 1 (NDOR1) is a diflavin reductase closely related to
cytochrome P450 reductase (POR) and nitric oxide synthase (NOS), which are involved in …

Objective: This study aimed to investigate the molecular mechanism underlying the
myeloperoxidase (MPO) induced apoptosis of human umbilical vein endothelial cells …

This chapter discusses disorders of folate metabolism and those of cobalamin metabolism,
and summarizes advances in the prenatal diagnosis of these disorders. The genes for all of …

Antecedente: la hiperhomocisteinemia es un factor de riesgo independiente de
aterosclerosis y aterotrombosis. Los individuos con la mutación 677 C> T en la 5, 10 …

Sulfur is found in relatively small quantities in biological molecules. It has numerous
properties that make it valuable in facilitating protein structure–function relationships that are …

Folate and cobalamin (vitamin B12) are B group vitamins that play interacting roles in
cellular metabolism. Hereditary folate malabsorption results in a specific deficiency of folate …