Advances in metal–organic framework-based nanozymes and their applications

X Huang, S Zhang, Y Tang, X Zhang, Y Bai… - Coordination Chemistry …, 2021 - Elsevier
Nanozymes bridge the fields of inorganic nanomaterials and biology and have attracted
wide attention. Nanozymes have the catalytic capabilities of inorganic materials at the …

Recent advances on endogenous/exogenous stimuli-triggered nanoplatforms for enhanced chemodynamic therapy

Q Sun, Z Wang, B Liu, F He, S Gai, P Yang… - Coordination Chemistry …, 2022 - Elsevier
In view of certain unique internalization features of the tumor microenvironment
(TME)(mainly including hypoxia, acidity and higher concentrations of H 2 O 2 and GSH) …

Engineered biomimetic nanoparticles achieve targeted delivery and efficient metabolism-based synergistic therapy against glioblastoma

G Lu, X Wang, F Li, S Wang, J Zhao, J Wang… - Nature …, 2022 - nature.com
Glioblastoma multiforme (GBM) is an aggressive brain cancer with a poor prognosis and few
treatment options. Here, building on the observation of elevated lactate (LA) in resected …

Strategies to engineer various nanocarrier-based hybrid catalysts for enhanced chemodynamic cancer therapy

JN Hao, K Ge, G Chen, B Dai, Y Li - Chemical Society Reviews, 2023 - pubs.rsc.org
Chemodynamic therapy (CDT) is a newly developed cancer-therapeutic modality that kills
cancer cells by the highly toxic hydroxyl radical (˙ OH) generated from the in situ triggered …

Metal-phenolic network-enabled lactic acid consumption reverses immunosuppressive tumor microenvironment for sonodynamic therapy

Z Zhang, B Li, L Xie, W Sang, H Tian, J Li, G Wang… - ACS …, 2021 - ACS Publications
Nanomedicine has revolutionized cancer therapeutic strategies but has not completely
changed the outcomes of tricky tumors that evolve a sophisticated immunosuppressive …

Lactate‐Oxidase‐Instructed Cancer Diagnosis and Therapy

S Jiang, X Chen, J Lin, P Huang - Advanced Materials, 2023 - Wiley Online Library
Lactate oxidase (LOx) has attracted extensive interest in cancer diagnosis and therapy in
recent years owing to its specific catalysis on l‐lactate; its catalytic process consumes …

Engineering lactate-modulating nanomedicines for cancer therapy

J Chen, Y Zhu, C Wu, J Shi - Chemical Society Reviews, 2023 - pubs.rsc.org
Lactate in tumors has long been considered “metabolic junk” derived from the glycolysis of
cancer cells and utilized only as a biomarker of malignancy, but is presently believed to be a …

L‐Arg‐Rich Amphiphilic Dendritic Peptide as a Versatile NO Donor for NO/Photodynamic Synergistic Treatment of Bacterial Infections and Promoting Wound Healing

J Zhu, J Tian, C Yang, J Chen, L Wu, M Fan, X Cai - Small, 2021 - Wiley Online Library
The development of alternative strategies for the efficient treatment of subcutaneous
abscesses that do not require the massive use of antibiotics and surgical intervention is …

Nanoplatform-based cascade engineering for cancer therapy

J Chen, Y Zhu, C Wu, J Shi - Chemical Society Reviews, 2020 - pubs.rsc.org
Various therapeutic techniques have been studied for treating cancer precisely and
effectively, such as targeted drug delivery, phototherapy, tumor-specific catalytic therapy …

Self‐activatable photo‐extracellular vesicle for synergistic trimodal anticancer therapy

J Ding, G Lu, W Nie, LL Huang, Y Zhang… - Advanced …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) hold great potential in both disease treatment and drug delivery.
However, accurate drug release from EVs, as well as the spontaneous treatment effect …