Drug delivery by supramolecular design

MJ Webber, R Langer - Chemical Society Reviews, 2017 - pubs.rsc.org
The rational design of drug delivery approaches leveraging supramolecular chemistry
(ie,“chemistry beyond the molecule”) has garnered significant interest in recent years toward …

Polymeric micelles for ocular drug delivery: From structural frameworks to recent preclinical studies

A Mandal, R Bisht, ID Rupenthal, AK Mitra - Journal of Controlled Release, 2017 - Elsevier
Effective intraocular drug delivery poses a major challenge due to the presence of various
elimination mechanisms and physiological barriers that result in low ocular bioavailability …

[HTML][HTML] Recent advances in nanotechnology for eradicating bacterial biofilm

C Sahli, SE Moya, JS Lomas, C Gravier-Pelletier… - Theranostics, 2022 - ncbi.nlm.nih.gov
Microorganisms grouped together into spatially-organized communities called biofilms, are
the cause of dramatic chronic infections in plants, animals and humans. In this review, the …

Cyclodextrin-based ocular drug delivery systems: A comprehensive review

Q Wang, A Zhang, L Zhu, X Yang, G Fang… - Coordination Chemistry …, 2023 - Elsevier
Cyclodextrin (CD), a class of cyclic oligosaccharides with an external hydrophilic surface
and a central hydrophobic cavity is recognized as a promising pharmaceutical excipient due …

COVID-19: a recommendation to examine the effect of mouthrinses with β-cyclodextrin combined with citrox in preventing infection and progression

F Carrouel, MP Conte, J Fisher, LS Gonçalves… - Journal of clinical …, 2020 - mdpi.com
Considered to be a major portal of entry for infectious agents, the oral cavity is directly
associated with the evolutionary process of SARS-CoV-2 in its inhalation of ambient …

Dexamethasone: insights into pharmacological aspects, therapeutic mechanisms, and delivery systems

VS Madamsetty, R Mohammadinejad… - ACS biomaterials …, 2022 - ACS Publications
Dexamethasone (DEX) has been widely used to treat a variety of diseases, including
autoimmune diseases, allergies, ocular disorders, cancer, and, more recently, COVID-19 …

Drug delivery approaches in addressing clinical pharmacology-related issues: opportunities and challenges

H Wen, H Jung, X Li - The AAPS journal, 2015 - Springer
Various drug delivery approaches can be used to maximize therapeutic efficacy and
minimize side effects, by impacting absorption, distribution, metabolism, and elimination …

Mesoporous silica materials: From physico-chemical properties to enhanced dissolution of poorly water-soluble drugs

A Maleki, H Kettiger, A Schoubben… - Journal of Controlled …, 2017 - Elsevier
New approaches in pharmaceutical chemistry have resulted in more complex drug
molecules in the quest to achieve higher affinity to their targets. However, these 'highly …

Nanotechnology-based antimicrobial and antiviral surface coating strategies

P Erkoc, F Ulucan-Karnak - Prosthesis, 2021 - mdpi.com
Biocontamination of medical devices and implants is a growing issue that causes medical
complications and increased expenses. In the fight against biocontamination, developing …

Resveratrol‐loaded nanomedicines for cancer applications

M Annaji, I Poudel, SHS Boddu, RD Arnold… - Cancer …, 2021 - Wiley Online Library
Abstract Background Resveratrol (3, 5, 4′‐trihydroxystilbene), a natural polyphenol and
phytoalexin, has drawn considerable attention in the past decade due to its wide variety of …