[HTML][HTML] Targeting the stem cell niche micro-environment as therapeutic strategies in aging

R Farahzadi, B Valipour, S Montazersaheb… - Frontiers in Cell and …, 2023 - frontiersin.org
Adult stem cells (ASCs) reside throughout the body and support various tissue. Owing to
their self-renewal capacity and differentiation potential, ASCs have the potential to be used …

The fission yeast mating-type switching motto:“one-for-two” and “two-for-one”

B Arcangioli, S Gangloff - Microbiology and Molecular Biology …, 2023 - Am Soc Microbiol
Schizosaccharomyces pombe is an ascomycete fungus that divides by medial fission; it is
thus commonly referred to as fission yeast, as opposed to the distantly related budding yeast …

[HTML][HTML] Differential condensation of sister chromatids acts with Cdc6 to ensure asynchronous S-phase entry in Drosophila male germline stem cell lineage

R Ranjan, J Snedeker, M Wooten, C Chu, S Bracero… - Developmental cell, 2022 - cell.com
During Drosophila melanogaster male germline stem cell (GSC) asymmetric division,
preexisting old versus newly synthesized histones H3 and H4 are asymmetrically inherited …

[HTML][HTML] A single N-terminal amino acid determines the distinct roles of histones H3 and H3.3 in the Drosophila male germline stem cell lineage

C Chandrasekhara, R Ranjan, JA Urban… - Plos …, 2023 - journals.plos.org
Adult stem cells undergo asymmetric cell divisions to produce 2 daughter cells with distinct
cell fates: one capable of self-renewal and the other committed for differentiation …

[HTML][HTML] Asymmetric cell division and tumor heterogeneity

Z Li, YY Zhang, H Zhang, J Yang, Y Chen… - Frontiers in Cell and …, 2022 - frontiersin.org
Asymmetric cell division (ACD) gives rise to two daughter cells with different fates after
mitosis and is a fundamental process for generating cell diversity and for the maintenance of …

Old and newly synthesized histones are asymmetrically distributed in Drosophila intestinal stem cell divisions

EH Zion, D Ringwalt, K Rinaldi, EW Kahney, Y Li… - EMBO …, 2023 - embopress.org
We report that preexisting (old) and newly synthesized (new) histones H3 and H4 are
asymmetrically partitioned during the division of Drosophila intestinal stem cells (ISCs) …

Wnt3a loaded deformable hydrogel acts as a 3D culture platform for in situ recruitment of stem cells to efficiently repair bone defects via the asymmetric division

Z Peng, S Niu, L Gui, X Kuang, F Li, B Chen… - Chemical Engineering …, 2022 - Elsevier
Biomaterial-based tissue engineering has emerged as a hotspot in the field of
osteanagenesis. Due to invasive operation in the transplantation process always bring …

[HTML][HTML] Quantitative RNA imaging in single live cells reveals age-dependent asymmetric inheritance

IV Kukhtevich, M Rivero-Romano, N Rakesh, P Bheda… - Cell reports, 2022 - cell.com
Asymmetric inheritance of cellular content through cell division plays an important role in cell
viability and fitness. The dynamics of RNA segregation are so far largely unaddressed. This …

Epigenetic regulation of asymmetric cell division by the LIBR-BRD4 axis

HF Chen, CT Chang, KW Hsu, PH Peng… - Nucleic Acids …, 2024 - academic.oup.com
Asymmetric cell division (ACD) is a mechanism used by stem cells to maintain the number of
progeny. However, the epigenetic mechanisms regulating ACD remain elusive. Here we …

[HTML][HTML] How stem cells remember their past

LN Royall, S Jessberger - Current opinion in cell biology, 2021 - Elsevier
Somatic stem cells are required for tissue development, homeostasis, and repair. Recent
data suggested that previous biographical experiences of individual stem cells influence …