Traumatic brain injury: progress and challenges in prevention, clinical care, and research

AIR Maas, DK Menon, GT Manley, M Abrams… - The Lancet …, 2022 - thelancet.com
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

National Institute of Neurological Disorders and Stroke consensus diagnostic criteria for traumatic encephalopathy syndrome

DI Katz, C Bernick, DW Dodick, J Mez, ML Mariani… - Neurology, 2021 - AAN Enterprises
Objective To develop evidence-informed, expert consensus research diagnostic criteria for
traumatic encephalopathy syndrome (TES), the clinical disorder associated with …

Applying the Bradford Hill criteria for causation to repetitive head impacts and chronic traumatic encephalopathy

CJ Nowinski, SC Bureau, ME Buckland… - Frontiers in …, 2022 - frontiersin.org
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with a
history of repetitive head impacts (RHI). CTE was described in boxers as early as the 1920s …

Management of moderate to severe traumatic brain injury: an update for the intensivist

G Meyfroidt, P Bouzat, MP Casaer, R Chesnut… - Intensive care …, 2022 - Springer
Traumatic brain injury (TBI) remains one of the most fatal and debilitating conditions in the
world. Current clinical management in severe TBI patients is mainly concerned with …

Thalamic deep brain stimulation in traumatic brain injury: a phase 1, randomized feasibility study

ND Schiff, JT Giacino, CR Butson, EY Choi, JL Baker… - Nature medicine, 2023 - nature.com
Converging evidence indicates that impairments in executive function and information-
processing speed limit quality of life and social reentry after moderate-to-severe traumatic …

Functional outcomes over the first year after moderate to severe traumatic brain injury in the prospective, longitudinal TRACK-TBI study

MA McCrea, JT Giacino, J Barber, NR Temkin… - JAMA …, 2021 - jamanetwork.com
Importance Moderate to severe traumatic brain injury (msTBI) is a major cause of death and
disability in the US and worldwide. Few studies have enabled prospective, longitudinal …

Mer regulates microglial/macrophage M1/M2 polarization and alleviates neuroinflammation following traumatic brain injury

H Wu, J Zheng, S Xu, Y Fang, Y Wu, J Zeng… - Journal of …, 2021 - Springer
Background Traumatic brain injury (TBI) is a leading cause of death and disability
worldwide. Microglial/macrophage activation and neuroinflammation are key cellular events …

Brain-gut axis dysfunction in the pathogenesis of traumatic brain injury

M Hanscom, DJ Loane… - The Journal of Clinical …, 2021 - Am Soc Clin Investig
Traumatic brain injury (TBI) is a chronic and progressive disease, and management requires
an understanding of both the primary neurological injury and the secondary sequelae that …

Microglia and neuroinflammation: crucial pathological mechanisms in traumatic brain injury-induced neurodegeneration

F Shao, X Wang, H Wu, Q Wu, J Zhang - Frontiers in Aging …, 2022 - frontiersin.org
Traumatic brain injury (TBI) is one of the most common diseases in the central nervous
system (CNS) with high mortality and morbidity. Patients with TBI usually suffer many …

[HTML][HTML] NODDI in clinical research

K Kamiya, M Hori, S Aoki - Journal of neuroscience methods, 2020 - Elsevier
Diffusion MRI (dMRI) has proven to be a useful imaging approach for both clinical diagnosis
and research investigating the microstructures of nervous tissues, and it has helped us to …